| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:MMP-2/MMP-9 Inhibitor II CAS:193807-60-2 Purity:>=98% Remarks:Reach out to us for more information about custom solutions.
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- BPHA
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- $179.00
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2026-05-06
- CAS:193807-60-2
- Purity: 99.44%
- Supply Ability: 10g
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| | MMP-9 Inhibitor II Basic information |
| Product Name: | MMP-9 Inhibitor II | | Synonyms: | Benzenepropanamide, α-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-N-hydroxy-, (αR)-;MMP-2/MMP-9 INHIBITOR II;MATRIX METALLOPROTEINASE-2/MATRIX METALLOPROTEINASE-9 INHIBITOR II;Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor II;BPHA, 10 mM in DMSO;(R)-2-([1,1'-Biphenyl]-4-sulfonamido)-N-hydroxy-3-phenylpropanamide | | CAS: | 193807-60-2 | | MF: | C21H20N2O4S | | MW: | 396.46 | | EINECS: | | | Product Categories: | | | Mol File: | 193807-60-2.mol |  |
| | MMP-9 Inhibitor II Chemical Properties |
| Melting point | 169-170 °C | | density | 1.309±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 100 mg/ml; Methanol: 25 mg/ml | | form | A solid | | pka | 9.03±0.40(Predicted) | | color | off-white |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | MMP-9 Inhibitor II Usage And Synthesis |
| Uses | MMP-2/MMP-9 Inhibitor II is a potent inhibitor of MMP-2 and MMP-9. | | Biological Activity | Cell permeable: no', 'Primary Target MMP-2', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 17 nM, 30 nM against MMP-2, and MMP-9, respectively | | in vivo | Daily oral administration of 200 mg/kg BPHA in mice results in potent inhibition of tumor-induced angiogenesis, primary tumor growth, and liver metastasis. The growth inhibition activity of BPHA is 48% and 45% in a B16-BL6 melanoma and F2 hemangio-endothelioma model, respectively[1]. | | IC 50 | MMP-2: 12 nM (IC50); MMP-9: 16 nM (IC50); MMP-14: 17 nM (IC50); MMP-1: 974 nM (IC50); MMP-3: >1000 nM (IC50); MMP-7: 795 nM (IC50) |
| | MMP-9 Inhibitor II Preparation Products And Raw materials |
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