黑色素聚集激素肽
| 中文名稱 | 黑色素聚集激素肽 |
|---|---|
| 中文同義詞 | 黑色素聚集激酶素(MCH;鮭魚黑色素聚集激素;黑色素聚集激素肽;黑素濃集素 |
| 英文名稱 | MELANIN CONCENTRATING HORMONE, SALMON |
| 英文同義詞 | MELANIN CONCENTRATING HORMONE;MELANIN CONCENTRATING HORMONE, SALMON;MCH (SALMON);ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL;ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL [DISULFIDE BRIDGE: 5-14];H-ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL-OH;ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL: DTMRCMVGRVYRPCWEV DISULFIDE BRIDGE CYS5-CYS14;Asp-Thr-Met-Arg-c[Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys]-Trp-Glu-Val |
| CAS號 | 87218-84-6 |
| 分子式 | C89H139N27O24S4 |
| 分子量 | 2099.5 |
| EINECS號 | |
| 相關類別 | 細胞生物學;標準品;目錄多肽;Peptide;Hormones;Neuropeptides;Obesity Research |
| Mol文件 | 87218-84-6.mol |
| 結構式 |  |
黑色素聚集激素肽 性質
| 密度 | 1.52±0.1 g/cm3(Predicted) |
|---|---|
| 儲存條件 | −20°C |
| 溶解度 | 溶于二甲基亞砜 |
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
| 序列 | Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val (Disulfide bridge: Cys5-Cys14) |
SLC-1/GPR24, MCHR2
An orphan G protein-coupled receptor (SLC-1/GPR24) has been identified as a receptor for MCH (MCHR1). MCHR2 has higher protein sequence homology to MCHR1 than any other G protein-coupled receptor. MCHR2 is specifically activated by nanomolar concentrations of MCH, binds to MCH with high affinity, and signals through Gq protein.
Melanin Concentrating Hormone stimulates appetite. Continuous infusion of Melanin Concentrating Hormone into the ventricular system increases food intake for 7-8 days. Intracerebroventricular infusion of Melanin Concentrating Hormone (10 μg/day) causes a slight but significant increase in body weight in mice maintained on the regular diet. Chronic stimulation of the brain Melanin Concentrating Hormone system could cause obesity in mice.
安全信息
| 安全說明 | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| 提供商 | 語言 |
|---|---|
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英文
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| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-P1525 | 黑色素聚集激素肽 Melanin Concentrating Hormone, salmon | 87218-84-6 | 1 mg | 900元 |
| 2026/06/05 | HY-P1525 | 黑色素聚集激素肽 Melanin Concentrating Hormone, salmon | 87218-84-6 | 5 mg | 2300元 |