SALICORTIN
| 中文名稱 | SALICORTIN |
|---|---|
| 中文同義詞 | 特里楊苷;化合物 T12828;柳皮苷;特里楊苷/酚類糖苷 |
| 英文名稱 | β-D-Glucopyranoside, 2-[[[[(1S)-1-hydroxy-6-oxo-2-cyclohexen-1-yl]carbonyl]oxy]methyl]phenyl |
| 英文同義詞 | β-D-Glucopyranoside, 2-[[[[(1S)-1-hydroxy-6-oxo-2-cyclohexen-1-yl]carbonyl]oxy]methyl]phenyl;Salicortin - Populus sp. (Poplar);β-D-Glucopyranoside, 2-[[[[(1S)-1-hydroxy-6-oxo-2-cyclohexen-1-yl]carbonyl]oxy]methyl]phenyl |
| CAS號(hào) | 1887055-63-1 |
| 分子式 | C20H24O10 |
| 分子量 | 424.4 |
| EINECS號(hào) | |
| 相關(guān)類別 | |
| Mol文件 | 1887055-63-1.mol |
| 結(jié)構(gòu)式 |  |
SALICORTIN 性質(zhì)
| 熔點(diǎn) | 141-142 °C |
|---|---|
| 沸點(diǎn) | 664.8±55.0 °C(Predicted) |
| 密度 | 1.531±0.06 g/cm3(Predicted) |
| 酸度系數(shù)(pKa) | 10.29±0.20(Predicted) |
Salicortin 是一種酚類糖苷，已從許多植物 (如胡楊和柳屬植物) 中分離出來。Salicortin 通過下調(diào) JNK 和 NF-κB/NFATc1 信號(hào)通路抑制破骨細(xì)胞分化和骨吸收。Salicortin 具有抗遺忘，抗脂肪形成和免疫調(diào)節(jié)活性。
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JNK
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NF-κB
|
Salicortin (100 μM; 2 hours) almost completely retards the phosphorylation of IκBα.
Western Blot Analysis
| Cell Line: | Mouse bone marrow macrophage (BMM) |
| Concentration: | 100 μM |
| Incubation Time: | 2 hours |
| Result: | Retarded the phosphorylation of IκBα. |