Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)-

Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)- Suppliers list
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:NVS-PI3-4
CAS:941580-60-5
Purity:99% Package:$250.9/5mg;$400.9/10mg;$850.9/25mg;Bulk package Remarks:99%
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:NVS-PI3-4
CAS:941580-60-5
Package:100mg;1590USD|25mg;766USD|50mg;995USD
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Products Intro: Product Name:NVS-PI3-4
CAS:941580-60-5
Purity:99% Remarks:Reach out to us for more information about custom solutions.
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 13636370518
Email: shyysw007@163.com
Products Intro: Product Name:NVS-PI3-4
CAS:941580-60-5
Package:1ml Remarks:T99990
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Products Intro: CAS:941580-60-5
Purity:98 Package:1G,5G,10G,50G,100G,500G

Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)- manufacturers

  • NVS-PI3-4
  • NVS-PI3-4 pictures
  • $1590.00
  • 2026-05-11
  • CAS:941580-60-5
  • Purity:
  • Supply Ability: 10g
Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)- Basic information
Product Name:Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)-
Synonyms:Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)-;NVS-PI3-4;NVS PI3 4,NVS-PI-3-4,NVSPI34;3-[[[[5-(4-Acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)propanamide
CAS:941580-60-5
MF:C20H26N4O3S
MW:402.51
EINECS:
Product Categories:
Mol File:941580-60-5.mol
Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)- Structure
Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)- Chemical Properties
density 1.211±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (621.10 mM; Need ultrasonic)
form Solid
pka6.48±0.70(Predicted)
color Off-white to yellow
Safety Information
MSDS Information
Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)- Usage And Synthesis
UsesNVS-PI3-4 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases[1][2].
Biological ActivityNVS-PI3-4 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases[1][2]. NVS-PI3-4 shows an exquisite cellular selectivity for PI3Kγ. NVS-PI3-4 reduces IgE/antigen-mediated phosphorylation of PKB/Akt in p110δDA. NVS-PI3-4 (5 μM; 30 minutes; BMMCs) is not accumulate in specifically in mast cells[2].
IC 50PI3Kγ
References[1]. Bruce I, et al. Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway. Bioorg Med Chem Lett. 2012;22(17):5445-5450. [2]. Collmann E, et al. Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells’ route to allergy. J Allergy Clin Immunol. 2013;132(4):959-968.
Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)- Preparation Products And Raw materials
Tag:Propanamide, 3-[[[[5-(4-acetylphenyl)-4-methyl-2-thiazolyl]amino]carbonyl]amino]-N-(1,1-dimethylethyl)-(941580-60-5) Related Product Information