| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:ZK187638
CAS:397298-63-4
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl- manufacturers
- ZK187638
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- $1980.00
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2026-04-21
- CAS:397298-63-4
- Purity:
- Supply Ability: 10g
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| | 11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl- Basic information |
| Product Name: | 11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl- | | Synonyms: | 11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl-;ZK187638 | | CAS: | 397298-63-4 | | MF: | C20H17N3O2 | | MW: | 331.37 | | EINECS: | | | Product Categories: | | | Mol File: | 397298-63-4.mol | ![11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl- Structure](CAS/20210305/GIF/397298-63-4.gif) |
| | 11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl- Chemical Properties |
| Melting point | 176.6 °C | | Boiling point | 560.3±60.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | pka | 7.77±0.40(Predicted) |
| | 11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl- Usage And Synthesis |
| Uses | ZK 187638 is an AMPA receptor antagonist. ZK 187638 antagonizes the kainate-induced currents in cultured hippocampal neurons with an IC50 of 3.4 μM in a noncompetitive fashion[1]. | | References | [1] Bernd Elger, et al. Novel alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonists of 2,3-benzodiazepine type: chemical synthesis, in vitro characterization, and in vivo prevention of acute neurodegeneration. J Med Chem. 2005 Jul 14;48(14):4618-27. DOI:10.1021/jm0580003 |
| | 11H-1,3-Dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine, 8,9-dimethyl-5-phenyl- Preparation Products And Raw materials |
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