ChemicalBook > Product Catalog >Natural Products >Xanthones >J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone

J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone

J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone Suppliers list
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-87569262 +86-15003564040
Email: 1056@dideu.com
Products Intro: Product Name:6-Deoxyjacareubin
CAS:16265-56-8
Purity:99%HPLC Package:1g;USD|10g;USD|100g;USD|25KG;USD|200KG;USD
Company Name: ANHUI WITOP BIOTECH CO., LTD
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Products Intro: Product Name:6-DEOXYJACAREUBIN
CAS:16265-56-8
Company Name: Labnetwork lnc.
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Products Intro: Product Name:6-Deoxyjacareubin
CAS:16265-56-8
Purity:95% Package:100g; 1kg Remarks:LN03258963
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:6-Deoxyjacareubin
CAS:16265-56-8
Package:1 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: BioBioPha Co., Ltd.  
Tel: 0871-65217109 13211707573;
Email: y.liu@mail.biobiopha.com
Products Intro: Product Name:6-Deoxyjacareubin
CAS:16265-56-8
Purity:98.0% Package:5mg Remarks:BBP03172

J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone manufacturers

  • 6-Deoxyjacareubin
  • 6-Deoxyjacareubin pictures
  • 2026-02-02
  • CAS:16265-56-8
  • Min. Order: 5mg
  • Purity: 99%HPLC
  • Supply Ability: 2000tons
J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone Basic information
Product Name:J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone
Synonyms:5,10-Dihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one;9-Deshydroxyjacareubin;J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone;6-Dehydroxyjacareubin;6-Desoxyjacareubin;5,10-dihydroxy-2,2-dimethylpyrano[3,2-b]xanthen-6-one;2H,6H-Pyrano[3,2-b]xanthen-6-one, 5,10-dihydroxy-2,2-dimethyl-;6-Deoxyjacareubin
CAS:16265-56-8
MF:C18H14O5
MW:310.3
EINECS:
Product Categories:
Mol File:16265-56-8.mol
J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone Structure
J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone Chemical Properties
Melting point 214-215℃
Boiling point 523.4±50.0 °C(Predicted)
density 1.410±0.06 g/cm3(Predicted)
pka6.59±0.40(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone Usage And Synthesis
Uses6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS)[1].
DefinitionChEBI: 6-Deoxyjacareubin is a member of pyranoxanthones.
in vivo

6-Deoxyjacareubin (5 mg/kg, i.p., every seven days for 1 month) attenuates motor neuron loss in familial ALS model mice[1].

Animal Model:Male SOD1G93A mice (eight weeks)[1]
Dosage:5 mg/kg
Administration:Intraperitoneally (i.p.), every seven days for 1 month
Result:Prolonged the survival time of SOD1G93A mice and improved their locomotor dysfunction. Suppressed glial activation and showed protective effect on motor neuron loss.
References[1] Hoshino T, et al. 6-Deoxyjacareubin, a natural compound preventing hypoxia-induced cell death, ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis. Neurosci Res. 2021 Feb;163:43-51. DOI:10.1016/j.neures.2020.02.011
J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone Preparation Products And Raw materials
Tag:J167.440D1,5-Dihydroxy-6',6'-dimethylpyrano[2',3':3,2]xanthone(16265-56-8) Related Product Information
6-CHLOROHEXANOYL CHLORIDE 6-Maleimidocaproic acid 6-Fluoroindole Xanthone Atroviridin 1-(5,7-Dimethoxy-2,2-dimethyl-2H-chromen-8-yl)ethanone