| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Niloticin
CAS:115404-57-4
Purity:98.0% Package:5mg Remarks:BBP00024
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| | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Basic information |
| Product Name: | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one | | Synonyms: | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one;Lanost-7-en-3-one,24,25-epoxy-23-hydroxy-, (13a,14b,17a,20S,23R,24S)-;Lanost-7-en-3-one, 24,25-epoxy-23-hydroxy-, (13α,14β,17α,20S,23R,24S)-;Niloticin | | CAS: | 115404-57-4 | | MF: | C30H48O3 | | MW: | 456.71 | | EINECS: | | | Product Categories: | Triterpenoids | | Mol File: | 115404-57-4.mol |  |
| | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Chemical Properties |
| Melting point | 149-151 °C | | Boiling point | 538.5±45.0 °C(Predicted) | | density | 1.07±0.1 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Cryst. | | pka | 14.37±0.20(Predicted) | | color | White to off-white |
| | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Usage And Synthesis |
| Uses | Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1]. | | References | [1] Xu H, et al. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. Biomed Pharmacother. 2022 May;149:112902. DOI:10.1016/j.biopha.2022.112902 |
| | (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one Preparation Products And Raw materials |
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