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| | 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Basic information |
| Product Name: | 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER | | Synonyms: | 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER;Ethyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylate;3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, ethyl ester;3-Carbethoxy-4-hydroxy-7-chloroquinoline;Ethyl 4-hydroxy-7-chloroquinoline-3-carboxylate;4-Hydroxy-7-chloroquinoline-3-carboxylic acid ethyl ester;Ethyl7-chloro-4-hydroxy-3-quinolinecarboxylate;NSC 403048 | | CAS: | 16600-22-9 | | MF: | C12H10ClNO3 | | MW: | 251.67 | | EINECS: | | | Product Categories: | | | Mol File: | 16600-22-9.mol |  |
| | 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties |
| Melting point | 296-298℃ | | Boiling point | 366.8±37.0 °C(Predicted) | | density | 1.386 | | storage temp. | Sealed in dry,Room Temperature | | pka | 2.18±0.50(Predicted) |
| | 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Usage And Synthesis |
| Chemical Properties | Crystalline compounds. Melting point 297 ℃. | | Uses | Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be used as an intermediate of chloroquine. | | Synthesis | Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be obtained by heating and condensing m-chloroaniline and triethyl orthoformate, then condensing with diethyl malonate with the participation of boron trifluoride, and finally heating and cyclizing in paraffin oil. |
| | 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials |
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