AMpkinone

AMpkinone Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Ampkinone
CAS:1233082-79-5
Purity:98.00% Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:AMpkinone
CAS:1233082-79-5
Purity:41999% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Ampkinone
CAS:1233082-79-5
Purity:98% Remarks:Please reach out to us for more information about custom solutions.
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:Ampkinone
CAS:1233082-79-5
Package:5mg;|10mg;
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:Ampkinone
CAS:1233082-79-5
Purity:95% Package:$73.9/1mg;$209.9/2.5mg;$220.9/5mg;$418.9/10mg;Bulk package Remarks:95%

AMpkinone manufacturers

  • Ampkinone
  • Ampkinone pictures
  • $797.00
  • 2026-07-27
  • CAS:1233082-79-5
  • Purity:
  • Supply Ability: 10g
  • Ampkinone
  • Ampkinone pictures
  • $797.00
  • 2026-07-27
  • CAS:1233082-79-5
  • Purity:
  • Supply Ability: 10g
  • Ampkinone
  • Ampkinone pictures
  • $797.00
  • 2025-08-22
  • CAS:1233082-79-5
  • Purity:
  • Supply Ability: 10g
AMpkinone Basic information
Product Name:AMpkinone
Synonyms:AMpkinone;[1]Benzopyrano[3,4-e]isoindole-1,3(2H,4H)-dione, 2-(4-benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl-;CS-2123;AMPK Activator V, Ampkinone
CAS:1233082-79-5
MF:C31H23NO6
MW:505.52
EINECS:
Product Categories:Aromatics, Amines, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:1233082-79-5.mol
AMpkinone Structure
AMpkinone Chemical Properties
Boiling point 732.7±70.0 °C(Predicted)
density 1.353±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≤2mg/ml in DMSO;10mg/ml in dimethyl formamide
form crystalline solid
pka9.01±0.40(Predicted)
color Light yellow to yellow
InChIKeyBRRCHDIWBKOMEC-UHFFFAOYSA-N
SMILESOC1=C(OC)C=CC2=C1OC(C)(C)C3=C2C=CC4=C3C(N(C5=CC=C(C(C6=CC=CC=C6)=O)C=C5)C4=O)=O
Safety Information
WGK Germany WGK 2
Storage Class11 - Combustible Solids
MSDS Information
AMpkinone Usage And Synthesis
UsesAmpkinone is a novel small molecule activator of AMP-activated protein kinase. Ampkinone was shown to exhibit antidiabetic and antiobesity effects.
Biological Activityampkinone is an ampk activator.adenosine 5'-monophosphate (amp) activated protein kinase (ampk) has considered as an promising target molecule for the treatment of metabolic disorders, such as obesity and type 2 diabetes.
in vitroampkinone was identified as an indirect ampk activator, which was derived from the small molecule library constructed by diversity-oriented synthesis. ampkinone was able to stimulate the phosphorylation of ampk through the indirect activation of ampk in various cell lines. moreover, ampkinone-mediated activation of ampk needed the activity of lkb1 and led to increased glucose uptake in muscle cells [1].
in vivoanimal study found that ampkinone-treated dio mice had significantly reduced total body weight and overall fat mass. histological examination and measurement of lipid parameters showed that ampkinone could effectively improve metabolic abnormalities. these results demonstrated that ampkinone had a potential as a new class of therapeutic agent for antidiabetic and antiobesity treatment through the indirect stimulation of ampk [1].
IC 50AMPK
references[1] oh, s. ,kim, s.j.,hwang, j.h., et al. antidiabetic and antiobesity effects of ampkinone (6f), a novel small molecule activator of amp-activated protein kinase. journal of medicinal chemistry 53, 7405-7413 (2010).
AMpkinone Preparation Products And Raw materials
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