ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Suppliers list
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
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Products Intro: Product Name:Apremilast Impurity 20
CAS:1384441-38-6
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +1-00000000000
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Products Intro: Product Name:O-Demethyl Apremilast
CAS:1384441-38-6
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Company Name: ANHUI WITOP BIOTECH CO., LTD
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Products Intro: Product Name:ApreMilast IMpurity K
CAS:1384441-38-6
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Products Intro: Product Name:O-Demethyl apremilast
CAS:1384441-38-6
Package:1g; 5g; 25g; 1kg; 5kg; 25kg
Company Name: ShenZhen H&D Pharmaceutical Technology Co., LTD
Tel: +86-18627948422
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Products Intro: Product Name:Apremilast Impurity QJ
CAS:1384441-38-6
Purity:98% Package:10mg;|25mg;|50mg

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide manufacturers
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Basic information
Product Name:(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Synonyms:O-Desmethyl Apremilast;N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide;Apremilast impurity HS093311;Apremilast Impurity K;Apremilast Impurity 4 (O-Desmethyl Apremilast);Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl-;N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide;(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide,Apremilast Impurity
CAS:1384441-38-6
MF:C21H22N2O7S
MW:446.48
EINECS:
Product Categories:
Mol File:1384441-38-6.mol
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Structure
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Chemical Properties
Boiling point 765.2±60.0 °C(Predicted)
density 1.450±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
form A crystalline solid
pka9.80±0.31(Predicted)
Stability:Hygroscopic
Major Applicationpharmaceutical small molecule
InChIKeyPEUJABWEZWJNBO-MRXNPFEDSA-N
SMILESC(NC1=CC=CC2=C1C(=O)N([C@@H](C1=CC=C(O)C(OCC)=C1)CS(C)(=O)=O)C2=O)(=O)C
Safety Information
MSDS Information
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Usage And Synthesis
UsesN-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide is a related compound of Apremilast (A729700), which isan oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide may be a useful compound for determining metabolic clearance of apremilast. Apremilast Impurity 7
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Preparation Products And Raw materials
Preparation Products(S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Tag:(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide(1384441-38-6) Related Product Information
1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone Apremilast Apremilast (S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide APST-ZA Apremilast Impurity E Apremilast Impurity 1 Apremilast (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt Apremilast Impurity 1/2 Apremilast Impurity 8 Apremilast Impurity 13 Apremilast Impurity 28 Apremilast Impurity 25 Apremilast-d8 3-acetamidophthalic acid Apremilast Impurity 2 Apremilast Impurity 9