| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:CHOLANIC ACID
CAS:25312-65-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:5-BETA-CHOLAN-24-OIC ACID
CAS:25312-65-6
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| | CHOLANIC ACID Basic information |
| | CHOLANIC ACID Chemical Properties |
| Melting point | 163-164°; mp 163.5° | | alpha | D20 +21.7° (chloroform) | | Boiling point | 432.57°C (rough estimate) | | density | 1.0086 (rough estimate) | | refractive index | 1.4480 (estimate) | | pka | 4.76±0.10(Predicted) | | Optical Rotation | +2220 (c 2, CHCl3) |
| | CHOLANIC ACID Usage And Synthesis |
| Definition | ChEBI: A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24. | | Purification Methods | Crystallise 5-cholanic acid from EtOH, Me2CO or AcOH. The ethyl ester has m 93-94o (from 80% EtOH), b 273o/12mm, [] D 20 +21o (CHCl3), and the methyl ester has m 86-87o (from MeOH) after purification through Al2O3 and eluting with *C6H6, and [] D 20 +21.2o (CHCl3). The 1H NMR (CDCl3) for the C18 & C19 protons has at 0.65 and 0.92ppm [see 5-cholanic acid above, Mandava et al. Steroids 23 357 1974]. [Stoll et al. Helv Chim Acta 18 644 1935, Huang-Minlon J Am Chem Soc 7 1 330 1949, Beilstein 9 III 2656, 9 IV 1992.] |
| | CHOLANIC ACID Preparation Products And Raw materials |
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