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| | TYRPHOSTIN AG 1288 Basic information |
| Product Name: | TYRPHOSTIN AG 1288 | | Synonyms: | TYRPHOSTIN AG 1288;(3,4-DIHYDROXY-5-NITROBENZYLIDENE) MALONONITRILE;ALPHA-CYANO-(3,4-DIHYDROXY-5-NITRO)CINNAMONITRILE;AG 1288;Propanedinitrile, 2-[(3,4-dihydroxy-5-nitrophenyl)methylene]-;2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile;TYRPHOSTIN AG 1288 USP/EP/BP | | CAS: | 116313-73-6 | | MF: | C10H5N3O4 | | MW: | 231.16 | | EINECS: | | | Product Categories: | | | Mol File: | 116313-73-6.mol |  |
| | TYRPHOSTIN AG 1288 Chemical Properties |
| storage temp. | −20°C | | form | Pale orange solid. | | color | Light yellow to yellow |
| | TYRPHOSTIN AG 1288 Usage And Synthesis |
| Uses | Tyrphostin AG 1288 is a potent Tyrosine Kinase inhibitor. Tyrphostin AG 1288 inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro[1]. | | Definition | ChEBI: 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile is a nitrophenol. | | References | [1] Burke-Gaffney A, et al. Tumour necrosis factor-alpha-induced ICAM-1 expression in human vascular endothelial and lung epithelial cells: modulation by tyrosine kinase inhibitors. Br J Pharmacol. 1996 Nov;119(6):1149-58. DOI:10.1111/j.1476-5381.1996.tb16017.x |
| | TYRPHOSTIN AG 1288 Preparation Products And Raw materials |
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