N2-[(N,N-Dimethylamino] methylene-N1-methyl-2'-O-methylguanosine
| 中文名稱 | N2-[(N,N-Dimethylamino] methylene-N1-methyl-2'-O-methylguanosine |
|---|---|
| 中文同義詞 | 化合物 N2-[(N,N-DIMETHYL)AMINO]METHYLENE-N1-METHYL-2'-O-METHYL GUANOSINE |
| 英文名稱 | N2-[(N,N-Dimethylamino] methylene-N1-methyl-2'-O-methylguanosine |
| 英文同義詞 | N2-[(N,N-Dimethylamino] methylene-N1-methyl-2'-O-methylguanosine;N2-[(N,N-Dimethylamino]methylene-N1-methyl-2’-O-methylguanosine;(E)-N'-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1-methyl-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide |
| CAS號 | 2305416-07-1 |
| 分子式 | C15H22N6O5 |
| 分子量 | 366.38 |
| EINECS號 | |
| 相關(guān)類別 | |
| Mol文件 | 2305416-07-1.mol |
| 結(jié)構(gòu)式 | ![N2-[(N,N-Dimethylamino] methylene-N1-methyl-2'-O-methylguanosine 結(jié)構(gòu)式](CAS/20211123/GIF/2305416-07-1.gif) |
N2-[(N,N-Dimethylamino] methylene-N1-methyl-2'-O-methylguanosine 性質(zhì)
| 沸點(diǎn) | 660.4±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.55±0.1 g/cm3(Predicted) |
| 酸度系數(shù)(pKa) | 13.20±0.70(Predicted) |
N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine 是一種鳥嘌呤核苷類似物。鳥嘌呤核苷類似物具有免疫刺激活性。在一些動(dòng)物模型中，它們還誘導(dǎo) I 型干擾素，產(chǎn)生抗病毒作用。研究表明，鳥苷類似物的功能活性依賴于活化 Toll 樣受體 7 (TLR7)。