伊維菌素B1B
| 中文名稱(chēng) | 伊維菌素B1B |
|---|---|
| 中文同義詞 | 伊維菌素B1B;伊維菌素雜質(zhì)2;依維菌素B1B;伊維菌素H2B1B |
| 英文名稱(chēng) | Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- |
| 英文同義詞 | Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-;avermectin H2B1b;Component B1b;22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a;22,23-Dihydroavermectin B1b;Dihydroavermectin B1b;5-O-Demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a |
| CAS號(hào) | 70209-81-3 |
| 分子式 | C47H72O14 |
| 分子量 | 861.07 |
| EINECS號(hào) | 274-384-5 |
| 相關(guān)類(lèi)別 | 微生物代謝物 |
| Mol文件 | 70209-81-3.mol |
| 結(jié)構(gòu)式 |  |
伊維菌素B1B 性質(zhì)
| 沸點(diǎn) | 934.1±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.24±0.1 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Store at -20°C |
| 溶解度 | DMF：可溶； DMSO：可溶；乙醇：可溶；甲醇：可溶 |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 12.42±0.70(Predicted) |
| 顏色 | White to off-white |
| 穩(wěn)定性 | 對(duì)溫度敏感 |
| InChIKey | VARHUCVRRNANBD-PVVXTEPVSA-N |
Ivermectin B1b 是 Ivermectin 的次要成分。Ivermectin 是一種有效的抗寄生蟲(chóng)藥物，可抑制 SARS-CoV-2 復(fù)制。
Ivermectin and Ivermectin B1b are the most potent inhibitors of contraction and motility in both susceptible isolates (
H. contortus
McMaster and and
O. circumcincta
McMaster) also show the highest resistance ratios in both species.
Vermectin is a macrocyclic lactone that acts as a positive allosteric modulator of α7 nicotinic acetylcholine receptors (nAChRs) but has no modulatory activity on 5-HT3 receptors.
Ivermectin B1b causes snail death.
安全信息
| 危險(xiǎn)品運(yùn)輸編號(hào) | 2588 |
|---|---|
| 危險(xiǎn)等級(jí) | 6.1(a) |
| 包裝類(lèi)別 | II |
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-125729 | 伊維菌素B1B Ivermectin B1b | 70209-81-3 | 500μg | 2200元 |
| 2026/06/05 | HY-125729 | 伊維菌素B1B Ivermectin B1b | 70209-81-3 | 1 mg | 3520元 |