| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:ML358
CAS:1158607-44-3
Package:100mg/RMB 17500;50mg/RMB 13800;25mg/RMB 10600
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Benzenemethanamine, 3-chloro-4-[(4-chlorophenyl)methoxy]-N-cyclopentyl-5-ethoxy-, hydrochloride (1:1) manufacturers
- ML358
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- $2500.00
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2026-05-11
- CAS:1158607-44-3
- Purity:
- Supply Ability: 10g
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| | Benzenemethanamine, 3-chloro-4-[(4-chlorophenyl)methoxy]-N-cyclopentyl-5-ethoxy-, hydrochloride (1:1) Basic information |
| | Benzenemethanamine, 3-chloro-4-[(4-chlorophenyl)methoxy]-N-cyclopentyl-5-ethoxy-, hydrochloride (1:1) Chemical Properties |
| | Benzenemethanamine, 3-chloro-4-[(4-chlorophenyl)methoxy]-N-cyclopentyl-5-ethoxy-, hydrochloride (1:1) Usage And Synthesis |
| Description | ML358 is a selective inhibitor of SKN-1 pathway involved in drug detoxification and resistance in nematodes. | | Uses | ML358 is a first in class, potent, and selective inhibitor of the SKN-1 pathway (IC50=0.24 μM). ML358 sensitizes the model nematode C. elegans to oxidants and anthelmintic. ML358 potentially used as adjuvants to increase the efficacy and useful life of current anthelmintics[1]. | | References | [1] Peddibhotla, S, et al.Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes. ACS Chemical Biology, 10(8), 1871–1879. DOI:10.1021/acschembio.5b00304 |
| | Benzenemethanamine, 3-chloro-4-[(4-chlorophenyl)methoxy]-N-cyclopentyl-5-ethoxy-, hydrochloride (1:1) Preparation Products And Raw materials |
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