- Beta-mangostin
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2026-06-08
- CAS:20931-37-7
- Min. Order: 10MG
- Purity: ≥98% HPLC
- Supply Ability: 100KG
- Beta-mangostin
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- $47.00
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2026-04-27
- CAS:20931-37-7
- Purity: 99.97%
- Supply Ability: 10g
- Beta-Mangostin
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- $180.00
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2025-04-15
- CAS:20931-37-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
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| | Beta-mangostin Basic information |
| Product Name: | Beta-mangostin | | Synonyms: | Beta-mangostin;1,6-Dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one;1,6-Dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one;Beta-mangostin
β-Mangostin;β-Mangostin, 98%, from Garcinia mangostana L.;beta-Mangostin, >98%;Keywords Dianthus extract;shanzhuguoduofen | | CAS: | 20931-37-7 | | MF: | C25H28O6 | | MW: | 424.49 | | EINECS: | 618-347-7 | | Product Categories: | reagent;standard substance | | Mol File: | 20931-37-7.mol |  |
| | Beta-mangostin Chemical Properties |
| Melting point | 175-176℃ | | Boiling point | 616.5±55.0 °C(Predicted) | | density | 1.212 | | storage temp. | 2-8°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder | | pka | 7.05±0.20(Predicted) | | color | Yellow | | Stability: | Light Sensitive |
| | Beta-mangostin Usage And Synthesis |
| Description | β-Mangostin is a xanthone originally isolated from G. mangostana with diverse biological activites. It inhibits growth of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA; MICs = 6.25-12.5 and 6.25-25 μg/ml, respectively), P. falciparum (IC50 = 3 μg/ml), and M. tuberculosis (MIC = 6.25 μg/ml). β-Mangostin inhibits fatty acid synthase (FASN) with an IC50 value of 24.83 μM. It induces cell cycle arrest at the G2/M phase and intrinsic and mitochondrial apoptosis in MCF-7 breast cancer cells. β-Mangostin also inhibits LPS-induced nitric oxide and prostaglandin E2 (PGE2; ) production in RAW264.7 cells and reduces neutrophil infiltration and TNF-α and IL-1β production in a mouse model of carrageenan-induced peritonitis. | | Uses | β-Mangostin is isolated from the stem bark of Garcinia mangostana L. which shows significant cytotoxicities and anti-inflammatory activities against the LPS-induced RAW cell 264.7. Also, it demonstrates anti-metastatic activity against human hepatocellular carcinoma (HCC) cells, which may act as a promising therapeutic agent for the treatment of HCC. | | Definition | ChEBI: Beta-Mangostin is a member of xanthones. | | IC 50 | Plasmodium | | References | [1] MUNEKAZU IINUMA. Antibacterial Activity of Xanthones from Guttiferaeous Plants against Methicillin-resistant Staphylococcus aureus[J]. Journal of Pharmacy and Pharmacology, 1996, 48 8: 861-865. DOI: 10.1111/j.2042-7158.1996.tb03988.x
[2] K LIKHITWITAYAWUID J K T Phadungcharoen. Antimalarial xanthones from Garcinia cowa.[J]. Planta medica, 1998, 64 1: 70-72. DOI: 10.1055/s-2006-957370
[3] SUNIT SUKSAMRARN. Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana.[J]. Chemical & pharmaceutical bulletin, 2003, 51 7: 857-859. DOI: 10.1248/cpb.51.857
[4] HE ZHONG JIANG . Fatty acid synthase inhibitors of phenolic constituents isolated from Garcinia mangostana[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 20 20: Pages 6045-6047. DOI: 10.1016/j.bmcl.2010.08.061
[5] SUVITHA SYAM . β-Mangostin induces p53-dependent G2/M cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway and NfkB suppression in MCF-7 cells[J]. Journal of Functional Foods, 2014, 6: Pages 290-304. DOI: 10.1016/j.jff.2013.10.018
[6] SUVITHA SYAM . β Mangostin suppress LPS-induced inflammatory response in RAW 264.7 macrophages in vitro and carrageenan-induced peritonitis in vivo[J]. Journal of ethnopharmacology, 2014, 153 2: Pages 435-445. DOI: 10.1016/j.jep.2014.02.051 |
| | Beta-mangostin Preparation Products And Raw materials |
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