1H-Indazole-5-carboxamide, N-(3,4-dichlorophenyl)-1-methyl- manufacturers
- PSB-1491
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- $48.00
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2026-07-14
- CAS:1619884-67-1
- Purity: 99.81%
- Supply Ability: 10g
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| | 1H-Indazole-5-carboxamide, N-(3,4-dichlorophenyl)-1-methyl- Basic information |
| | 1H-Indazole-5-carboxamide, N-(3,4-dichlorophenyl)-1-methyl- Chemical Properties |
| Boiling point | 404.0±40.0 °C(Predicted) | | density | 1.43±0.1 g/cm3(Predicted) | | pka | 11.77±0.70(Predicted) |
| | 1H-Indazole-5-carboxamide, N-(3,4-dichlorophenyl)-1-methyl- Usage And Synthesis |
| Description | PSB-1491 is a potent, selective, competitive, and reversible inhibitor of monoamine oxidase B (MAO-B). | | Uses | PSB-1491 is a selective and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 of 0.386 nM for hMAO-B. PSB-1491 shows >25000-fold selective versus MAO-A[1]. | | IC 50 | hMAO-B: 0.0386 nM (IC50) | | References | [1] Tzvetkov NT, et al. Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57(15):6679-703. DOI:10.1021/jm500729a |
| | 1H-Indazole-5-carboxamide, N-(3,4-dichlorophenyl)-1-methyl- Preparation Products And Raw materials |
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