| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:STING agonist-10 CAS:2259308-69-3 Package:1removed
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| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Product Name:STING agonist-10 CAS:2259308-69-3
|
7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)- manufacturers
- STING agonist-10
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- $2785.00
-
2026-05-11
- CAS:2259308-69-3
- Purity:
- Supply Ability: 10g
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| | 7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)- Basic information |
| Product Name: | 7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)- | | Synonyms: | 7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)-;STING agonist-10 | | CAS: | 2259308-69-3 | | MF: | C25H20ClF4N3O2 | | MW: | 505.89 | | EINECS: | | | Product Categories: | | | Mol File: | 2259308-69-3.mol | ![7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)- Structure](CAS/20210305/GIF/2259308-69-3.gif) |
| | 7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)- Chemical Properties |
| Boiling point | 581.9±50.0 °C(Predicted) | | density | 1.393±0.06 g/cm3(Predicted) | | pka | 13.30±0.40(Predicted) |
| | 7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)- Usage And Synthesis |
| Uses | STING agonist-10 (Compound 91) is a potent small molecule cyclic urea activator of STING with the EC50 of 2600 nM. Activation of STING is a highly promising approach in immunotherapy[1]. | | References | [1] Sourav Basu, et al. The discovery of potent small molecule cyclic urea activators of STING. Eur J Med Chem. 2022 Feb 5;229:114087. DOI:10.1016/j.ejmech.2021.114087 |
| | 7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)- Preparation Products And Raw materials |
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