| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:GV-196771A
CAS:166974-23-8
Purity:>=95% Remarks:Reach out to us for more information about custom solutions.
|
| Company Name: |
MedChemexpress LLC
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:GV-196771A
CAS:166974-23-8
Purity:>98% Package:10200RMB/1mg
|
sodium 4,6-dichloro-3-[(E)-(2-oxo-1-phenyl-pyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylate manufacturers
- GV-196771A
-
- $700.00
-
2026-05-11
- CAS:166974-23-8
- Purity: 96.43%
- Supply Ability: 10g
- GV-196771A
-
- $700.00
-
2025-07-20
- CAS:166974-23-8
- Purity: 96.43%
- Supply Ability: 10g
|
| | sodium 4,6-dichloro-3-[(E)-(2-oxo-1-phenyl-pyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylate Basic information |
| | sodium 4,6-dichloro-3-[(E)-(2-oxo-1-phenyl-pyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylate Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | sodium 4,6-dichloro-3-[(E)-(2-oxo-1-phenyl-pyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylate Usage And Synthesis |
| Uses | GV-196771A is the sodium salt form of GV196771, is an NMDA receptor antagonist. | | in vivo | GV196771 is a potent antagonist of the modulatory glycine site of the N-methyl-D-aspartate receptor. GV196771 is a potent antagonist of the modulatory glycine site of the NMDA receptor developed for treatment of neuropathic pain. GV196771 is an NMDA receptor antagonist with low oral bioavailability in rats and mice. GV196771 has low oral bioavailability (<10%) and plasma clearance (~2 mL/min/kg) in rats[1]. | | IC 50 | NMDA Receptor | | References | [1] Polli JW, et al. The systemic exposure of an N-methyl-D-aspartate receptor antagonist is limited in mice by the P-glycoprotein and breast cancer resistance protein efflux transporters. Drug Metab Dispos. 2004 Jul;32(7):722-6. DOI:10.1124/dmd.32.7.722 |
| | sodium 4,6-dichloro-3-[(E)-(2-oxo-1-phenyl-pyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylate Preparation Products And Raw materials |
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