去氧穿心蓮內(nèi)酯
| 中文名稱 | 去氧穿心蓮內(nèi)酯 |
|---|---|
| 中文同義詞 | 去氧脫水穿心蓮內(nèi)酯;脫氧脫水穿心蓮內(nèi)酯;穿心蓮內(nèi)酯雜質(zhì)8;去氧脫水穿心蓮內(nèi)酯 標(biāo)準(zhǔn)品;14一去氧穿心蓮內(nèi)酯;14-去氧穿心蓮內(nèi)酯,10 MM DMSO 溶液;14-去氧穿心蓮內(nèi)酯, 分析對(duì)照品，＞98%;14-去氧穿心蓮內(nèi)酯, 分析對(duì)照品,>98% |
| 英文名稱 | 3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one |
| 英文同義詞 | 3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone;AD 04130-4;3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one;3-[2-[(1R,4aβ)-Decahydro-6α-hydroxy-5α-hydroxymethyl-5,8aα-dimethyl-2-methylenenaphthalen-1α-yl]ethyl]furan-2(5H)-one;3-{2-[(1R,4aS,5R,6R,8aS)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethy l-2-methylenedecahydro-1-naphthalenyl]ethyl}-2(5H)-furanone;2(5H)-Furanone,3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-;Andrographolide Impurity 8;platelet activating factor,rat,bovine neutrophils,14 Deoxyandrographolide,Calcium Channel,inhibit,14-Deoxyandrographolide,Ca channels,uterine smooth muscle,Inhibitor,14Deoxyandrographolide,Ca2+ channels |
| CAS號(hào) | 4176-97-0 |
| 分子式 | C20H30O4 |
| 分子量 | 334.45 |
| EINECS號(hào) | 2017-001-1 |
| 相關(guān)類別 | 標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品 -中藥標(biāo)準(zhǔn)品 |
| Mol文件 | 4176-97-0.mol |
| 結(jié)構(gòu)式 |  |
去氧穿心蓮內(nèi)酯 性質(zhì)
| 熔點(diǎn) | 176-178℃ |
|---|---|
| 沸點(diǎn) | 509.5±50.0 °C(Predicted) |
| 密度 | 1.15 |
| 儲(chǔ)存條件 | Store at -20°C |
| 溶解度 | 可溶于乙腈 |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 14.89±0.70(Predicted) |
| 顏色 | 白色至米白色 |
| InChI | InChI=1S/C20H30O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h9,15-17,21-22H,1,4-8,10-12H2,2-3H3/t15-,16+,17-,19+,20+/m1/s1 |
| InChIKey | GVRNTWSGBWPJGS-YSDSKTICSA-N |
| SMILES | O1CC=C(CC[C@H]2[C@@]3(C)[C@@]([H])([C@@](CO)(C)[C@H](O)CC3)CCC2=C)C1=O |
14-Deoxyandrographolide 是 Andrographis paniculata 的生物活性成分，具有保護(hù)肝臟的作用。14-Deoxyandrographolide 通過誘導(dǎo) TNFRSF1A 的釋放，逐漸使肝細(xì)胞對(duì) TNF-α 介導(dǎo)的凋亡脫敏。
化學(xué)性質(zhì)
白色粉末，可溶于甲醇、乙醇、DMSO等有機(jī)溶劑，來源于穿心蓮Andrographis paniculata (Burm. f.) Nees。用途
用于含量測(cè)定/鑒定/藥理實(shí)驗(yàn)等。安全信息
| WGK Germany | WGK 3 |
|---|---|
| 存儲(chǔ)類別 | 11 - 可燃固體 |