利培酮雜質(zhì)B 基本信息
| 中文名稱 | 利培酮雜質(zhì)B |
|---|---|
| 中文同義詞 | 利培酮EP雜質(zhì)B;Risperidone EP Impurity B Z式;利培酮Z肟;利培酮雜質(zhì)B (EP/BP);RISPERIDONE EP IMPURITY B Z式;利培酮雜質(zhì)B(EP) 標(biāo)準(zhǔn)品;利培酮雜質(zhì)B (Z異構(gòu)體);利培酮雜質(zhì)1282 |
| 英文名稱 | 3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one |
| 英文同義詞 | Risperidone Z-OxiMe IMpurity;Risperidone IMpurity B;Risperidone EP IMpurity B;3-[2-[4-[(Z)-(2,4-difluorophenyl)(hydroxyimino)methyl]piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one;(Z)-3-(2-(4-((2,4-difluorophenyl)(hydroxyimino)methyl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one;Risperidone Impurity 1(Risperidone EP Impurity B);3-[2-[4-[(Z)-C-(2,4-difluorophenyl)-N-hydroxycarbonimidoyl]piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one;Risperidone EP Imp B |
| CAS號(hào) | 132961-05-8 |
| 分子式 | C23H28F2N4O2 |
| 分子量 | 430.49 |
| EINECS號(hào) | 603-689-1 |
| 相關(guān)類別 | Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics |
| Mol文件 | 132961-05-8.mol |
| 結(jié)構(gòu)式 |  |
利培酮雜質(zhì)B 性質(zhì)
| 沸點(diǎn) | 569.0±60.0 °C(Predicted) |
|---|---|
| 密度 | 1.34±0.1 g/cm3(Predicted) |
| 蒸氣壓 | 0-0Pa at 20-25℃ |
| 溶解度 | 可溶于氯仿（少許）、甲醇（少許） |
| 形態(tài) | 固體：顆粒/粉末 |
| 酸度系數(shù)(pKa) | 11.20±0.28(Predicted) |
| 主要應(yīng)用 | pharmaceutical small molecule |
| LogP | 0.6-2.1 at 20℃ and pH6.9-10.4 |