| Company Name: |
CHINA ISOTOPE CO., LIMITED
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| Tel: |
02151600108 13062666369 |
| Email: |
info@isotopechem.com |
| Products Intro: |
Product Name:Dantrolene-d4
CAS:2749234-17-9
Purity:Purity: >=98% Package:1mg Remarks:CA29451
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Dantrolene-d4
CAS:2749234-17-9
Purity:95% Package:1mg
|
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| | Dantrolene-d4 Basic information |
| | Dantrolene-d4 Chemical Properties |
| | Dantrolene-d4 Usage And Synthesis |
| Uses | Dantrolene-D4 is the deuterium labelled analogue of Dantrolene Sodium Salt Hemiheptahydrate (D185000), which is a (skeletal) muscle relaxant, used in the treatment of malignant hyperthermia. | | References | [1] MD S K, PHD Masafumi Y M, PHD , et al. Dantrolene, a Therapeutic Agent for Malignant Hyperthermia, Markedly Improves the Function of Failing Cardiomyocytes by Stabilizing Interdomain Interactions Within the Ryanodine Receptor[J]. Journal of the American College of Cardiology, 2009, 53 21: Pages 1993-2005. DOI: 10.1016/j.jacc.2009.01.065
[2] YE WIN OO. Essential Role of Calmodulin in RyR Inhibition by Dantrolene.[J]. Molecular Pharmacology, 2015, 88 1: 57-63. DOI: 10.1124/mol.115.097691
[3] B A KOTSIAS S M. Reversible effect of dantrolene sodium on twitch tension of rat skeletal muscle.[J]. Archives of neurology, 1978, 35 4: 234-236. DOI: 10.1001/archneur.1978.00500280052010
[4] T E NELSON E H F. Rationale for dantrolene vs. procainamide for treatment of malignant hyperthermia.[J]. Anesthesiology, 1979, 50 2: 118-122. DOI: 10.1097/00000542-197902000-00008 |
| | Dantrolene-d4 Preparation Products And Raw materials |
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