甲氨蝶呤雜質(zhì) 基本信息
| 中文名稱(chēng) | 甲氨蝶呤雜質(zhì) |
|---|---|
| 中文同義詞 | 甲氨蝶呤 1-甲醚;甲氨蝶呤雜質(zhì)I(EP);甲氨蝶呤EP雜質(zhì)I(甲氨蝶呤-1-單甲基酯);甲氨蝶呤EP雜質(zhì)I;甲氨蝶呤雜質(zhì)9;METHOTREXATE EP雜質(zhì) I;甲氨蝶呤雜質(zhì)09;甲氨蝶呤ALPHA-甲酯 |
| 英文名稱(chēng) | Methotrexate α-Methyl Ester |
| 英文同義詞 | Methotrexate EP Impurity I（Amethopterin EP Impurity I）;(4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid;Methotrexate EP Impurity I/Methotrexate 1-Methyl Ester/Methotrexate α-Methyl Ester/(4S)-4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid;Methotrexate EP Impurity I (Methotrexate-1-Monomethyl Ester);Methotrexate-1-monomethyl ester;Methotrexate Impurity I;L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-methyl ester;(S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid |
| CAS號(hào) | 66147-29-3 |
| 分子式 | C21H24N8O5 |
| 分子量 | 468.47 |
| EINECS號(hào) | |
| 相關(guān)類(lèi)別 | 雜質(zhì)對(duì)照品;145-甲氨蝶呤;Aromatics, Chiral Reagents, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals |
| Mol文件 | 66147-29-3.mol |
| 結(jié)構(gòu)式 |  |
甲氨蝶呤雜質(zhì) 性質(zhì)
| 密度 | 1.459±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
|---|---|
| 溶解度 | 堿性溶液（微溶）、DMSO（微溶、加熱）、甲醇（微溶） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 4.429±0.10(predicted) |
| 顏色 | 淺黃色至深橙色 |