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Product Name:GLPG0492 R enantiomer
CAS:1215085-93-0
Purity:98% Remarks:Reach out to us for more information about custom solutions.
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GLPG0492 (R enantiomer) manufacturers
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| | GLPG0492 (R enantiomer) Basic information |
| Product Name: | GLPG0492 (R enantiomer) | | Synonyms: | GLPG0492 (R enantiomer);GLPG-0492 R enantiomer
(GLPG0492 R enantiomer);Benzonitrile, 4-[(4R)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)- | | CAS: | 1215085-93-0 | | MF: | C19H14F3N3O3 | | MW: | 389.33 | | EINECS: | | | Product Categories: | | | Mol File: | 1215085-93-0.mol |  |
| | GLPG0492 (R enantiomer) Chemical Properties |
| Boiling point | 544.0±60.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 13.50±0.10(Predicted) | | color | White to off-white |
| | GLPG0492 (R enantiomer) Usage And Synthesis |
| Uses | GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator. | | References | [1] Nique F, et al. Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator. J Med Chem. 2012 Oct 11;55(19):8236-47. DOI:10.1021/jm300281x
[2] Cozzoli A, et al. GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy. Pharmacol Res. 2013 Jun;72:9-24. DOI:10.1016/j.phrs.2013.03.003
[3] Blanqué R, et al. Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization. BMC Musculoskelet Disord. 2014 Sep 3;15:291. DOI:10.1186/1471-2474-15-291 |
| | GLPG0492 (R enantiomer) Preparation Products And Raw materials |
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