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KR-33494

KR-33494 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:4-(2-(4-bromophenylthio)acetamido)-1-phenethyl-1H-pyrazole-3-carboxylic acid
CAS:1021497-97-1
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:KR-33494
CAS:1021497-97-1
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471;
Email: sales@sarms4muscle.com
Products Intro: Product Name:KR-33494
CAS:1021497-97-1
Purity:99% Package:5KG;1KG Remarks:KR-33494
Company Name: Hong Kong Tiansheng New Material Trading Co., Ltd
Tel: +8617320695765
Email: zxx@hktiansheng.com
Products Intro: Product Name:KR-33494
CAS:1021497-97-1
Purity:99% Package:1Kg/Bag;100USD
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:KR-33494
CAS:1021497-97-1
Purity:98% Package:5mg Remarks:V23299

KR-33494 manufacturers

  • KR-33493
  • KR-33493 pictures
  • $34.00
  • 2026-05-11
  • CAS:1021497-97-1
  • Purity: 99.96%
  • Supply Ability: 10g
  • KR-33494
  • KR-33494 pictures
  • 2025-12-25
  • CAS:1021497-97-1
  • Min. Order: 1gram
  • Purity: 99%
  • Supply Ability: 10kg
  • KR-33494
  • KR-33494 pictures
  • $100.00
  • 2022-02-25
  • CAS:1021497-97-1
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 100KG
KR-33494 Basic information
Product Name:KR-33494
Synonyms:KR-33494;4-(2-(4-bromophenylthio)acetamido)-1-phenethyl-1H-pyrazole-3-carboxylic acid;KR-33493;4-[2-(4-bromo-phenylsulfanyl)-acetylamino]-1-phenethyl-1H-pyrazole-3-carboxylic acid;CS-2472;KR33494;KR 33494;1H-Pyrazole-3-carboxylic acid, 4-[[2-[(4-bromophenyl)thio]acetyl]amino]-1-(2-phenylethyl)-;4-[[2-[(4-Bromophenyl)thio]acetyl]amino]-1-(2-phenylethyl)-1H-pyrazole-3-carboxylic acid
CAS:1021497-97-1
MF:C20H18BrN3O3S
MW:460.34
EINECS:
Product Categories:
Mol File:1021497-97-1.mol
KR-33494 Structure
KR-33494 Chemical Properties
storage temp. Store at -20°C
solubility DMSO:61.5(Max Conc. mg/mL);133.6(Max Conc. mM)
form A crystalline solid
color White to off-white
Safety Information
MSDS Information
KR-33494 Usage And Synthesis
UsesKR-33493 is a potent inhibitor of Fas-mediated cell death (FAF1).
in vivo

Body weight changes of both sexes are not related to KR-33493 in all doses. In rats administrated KR-33493 for 4 weeks, no test article-related changes in any treated groups of either sex are found in hematology, serum biochemistry, and urinalysis. In dogs administrated KR-33493 for 2 weeks, red blood cell count (RBC) value in males is significantly higher at the 1000 mg/kg/day dose than that of the control group (i.e., 6.96±0.323 vs. 6.12±0.418). However, the change of RBC is recovered after the end of the administration period. The dose-normalized AUClast is not significantly different between the groups, suggesting that KR-33493 is governed by linear kinetics[1].

IC 50Fas
References[1] Jeong JW, et al. Subacute toxicity evaluation of KR-33493, FAF1 inhibitor for a new anti-parkinson's disease agent, after oral administration in rats and dogs. Regul Toxicol Pharmacol. 2016 Nov;81:387-396. DOI:10.1016/j.yrtph.2016.09.022
KR-33494 Preparation Products And Raw materials
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