ML 18

ML 18 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:ML 18
CAS:1422269-30-4
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:ML-18
CAS:1422269-30-4
Purity:98.53% Package:1mg;30USD|5mg;58USD|10mg;93USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:ML18
CAS:1422269-30-4
Purity:98% Package:5mg Remarks:V4011
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:ML-18；ML 18
CAS:1422269-30-4
Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054
Email: trendseenbio@gmail.com
Products Intro: Product Name:(2S)-3-(1H-INDOL-3-YL)-N-{[1-(4-METHOXYPHENYL)CYCLOHEXYL]METHYL}-2-{[(4-NITROPHENYL)CARBAMOYL]AMINO}PROPANAMIDE
CAS:1422269-30-4
Purity:99% Package:1kg；25kg

ML 18 manufacturers

  • ML-18
  • ML-18 pictures
  • $30.00
  • 2026-05-11
  • CAS:1422269-30-4
  • Purity: 98.62%
  • Supply Ability: 10g
ML 18 Basic information
Product Name:ML 18
Synonyms:ML 18;BRS-3 antagonist;ML18;ML-18;ML 18;BRS-3 ANTAGONIST;1422269-30-4;ML18, >98%;(2S)-3-(1H-INDOL-3-YL)-N-{[1-(4-METHOXYPHENYL)CYCLOHEXYL]METHYL}-2-{[(4-NITROPHENYL)CARBAMOYL]AMINO}PROPANAMIDE;(S)-3-(1H-Indol-3-yl)-N-((1-(4-methoxyphenyl)cyclohexyl)methyl)-2-(3-(4-nitrophenyl)ureido)propanamide;Bombesin Receptor,ML-18,ML 18,inhibit,Inhibitor,ML18;ML-18, 10 mM in DMSO
CAS:1422269-30-4
MF:C32H35N5O5
MW:569.66
EINECS:
Product Categories:
Mol File:1422269-30-4.mol
ML 18 Structure
ML 18 Chemical Properties
Boiling point 821.8±65.0 °C(Predicted)
density 1.291±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble
form A solid
pka11.99±0.46(Predicted)
color White to yellow
Safety Information
MSDS Information
ML 18 Usage And Synthesis
DescriptionML-18 is a non-peptide bombesin receptor subtype 3 (BB3) antagonist that inhibits [125I]BA1 binding to NCI-H1299 lung cancer cells transfected with human BB3 receptors (IC50 = 4.8 μM). It is selective for BB3 over the gastrin releasing peptide receptor (GRPR) and the neuromedin B receptor (NMBR) with IC50 values of 16 and >100 μM, respectively, in a radioligand binding assay. ML-18 (16 μM) reversibly inhibits BA1-induced increases in cytosolic calcium in NCI-H1299 cells. It also inhibits BA1-induced phosphorylation of ERK and EGFR and reduces proliferation of NCI-H1299 cells.
UsesML-18 is a non-peptide bombesin receptor subtype-3 antagonist. It also inhibits lung cancer growth.
References[1] TERRY W. MOODY . ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth[J]. Peptides, 2015, 64: Pages 55-61. DOI: 10.1016/j.peptides.2014.12.005
ML 18 Preparation Products And Raw materials
Tag:ML 18(1422269-30-4) Related Product Information
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