ethyl (2-(5-nitrothiophene-2-carboxamido)thiophene-3-carbonyl)carbamate manufacturers
- EACC
-
- $50.00
-
2026-05-11
- CAS:864941-31-1
- Purity: 99.80%
- Supply Ability: 10g
- EACC
-
- $50.00
-
2026-05-11
- CAS:864941-31-1
- Purity: 99.80%
- Supply Ability: 10g
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| | ethyl (2-(5-nitrothiophene-2-carboxamido)thiophene-3-carbonyl)carbamate Basic information |
| Product Name: | ethyl (2-(5-nitrothiophene-2-carboxamido)thiophene-3-carbonyl)carbamate | | Synonyms: | ethyl (2-(5-nitrothiophene-2-carboxamido)thiophene-3-carbonyl)carbamate;Carbamic acid, [[2-[[(5-nitro-2-thienyl)carbonyl]amino]-3-thienyl]carbonyl]-, ethyl ester (9CI);Autophagy,EACC,Inhibitor,inhibit;Carbamic acid, N-[[2-[[(5-nitro-2-thienyl)carbonyl]amino]-3-thienyl]carbonyl]-, ethyl ester;EACC, 10 mM in DMSO;EACC | | CAS: | 864941-31-1 | | MF: | C13H11N3O6S2 | | MW: | 369.37 | | EINECS: | | | Product Categories: | | | Mol File: | 864941-31-1.mol |  |
| | ethyl (2-(5-nitrothiophene-2-carboxamido)thiophene-3-carbonyl)carbamate Chemical Properties |
| density | 1.565±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 16.88 mg/mL (45.70 mM) | | form | Solid | | pka | 10.36±0.46(Predicted) | | color | Light yellow to yellow |
| | ethyl (2-(5-nitrothiophene-2-carboxamido)thiophene-3-carbonyl)carbamate Usage And Synthesis |
| Uses | EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion[1]. | | References | [1] Vats S, et al. A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes. Mol Biol Cell. 2019 Aug 1;30(17):2283-2295. DOI:10.1091/mbc.E18-08-0482 |
| | ethyl (2-(5-nitrothiophene-2-carboxamido)thiophene-3-carbonyl)carbamate Preparation Products And Raw materials |
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