DM4-SPDP

DM4-SPDP Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:DM4-SPDP
CAS:2245698-48-8
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:DM4-SPDP
CAS:2245698-48-8
Purity:>=98% Package:1 mg Remarks:Please reach out to us for more information about custom solutions.
Company Name: Hangzhou Huarong Pharm Co., Ltd.
Tel: 571-86758373 +8613588754946
Email: sales@huarongpharm.com
Products Intro: Product Name:DM4-SPDP
CAS:2245698-48-8
Purity:0.99 Package:10MG,50MG,100MG,1G
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 18892239720
Email: psaitong@jm-bio.com
Products Intro: Product Name:DM4-SPDP
CAS:2245698-48-8
Package:10mg;25mg;50mg
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:DM4-SPDP
CAS:2245698-48-8
Purity:97.0% Package:5mg
DM4-SPDP Basic information
Product Name:DM4-SPDP
Synonyms:DM4-SPDP;Maytansine, N2'-deacetyl-N2'-[4-[[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-4-methyl-1-oxopentyl]-
CAS:2245698-48-8
MF:C45H61ClN4O14S2
MW:981.57
EINECS:
Product Categories:
Mol File:2245698-48-8.mol
DM4-SPDP Structure
DM4-SPDP Chemical Properties
density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka9.82±0.70(Predicted)
Safety Information
MSDS Information
DM4-SPDP Usage And Synthesis
Uses(R)-DM4-SPDP is a conjugate made up of the linker SPDP and the toxic molecule DM4, and it can be used to prepare antibody-drug conjugates[1].
References[1] Silvana T Tivadar, et al. Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential. Mol Cancer Ther. 2020 Mar;19(3):790-801. DOI:10.1158/1535-7163.MCT-19-0221
DM4-SPDP Preparation Products And Raw materials
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