乳清酸鋅二水合物
| 中文名稱 | 乳清酸鋅二水合物 |
|---|---|
| 中文同義詞 | 乳清酸 鋅鹽 二水合物;乳清酸鋅二水合物;乳清酸鋅二水合物|乳清酸鋅;乳清酸鋅【乳清酸鋅二水合物】;ZINC(II) 2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN E-4-CARBOXYLATE;2,6-二氧代-1,2,3,6-四氫嘧啶-4-羧酸鋅鹽 |
| 英文名稱 | OROTIC ACID ZINC SALT DIHYDRATE |
| 英文同義詞 | OROTIC ACID ZINC SALT DIHYDRATE;1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicacizincsalt(2:1);zinc 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate (1:2);Zincorotate2H2O;Orotic acid dihydrate zinc salt;Bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid)zinc salt;Bis(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid) zinc salt;zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate |
| CAS號 | 68399-76-8 |
| 分子式 | C5H4N2O4Zn |
| 分子量 | 221.48 |
| EINECS號 | 269-988-0 |
| 相關(guān)類別 | 醫(yī)藥原料;營養(yǎng)增補劑;農(nóng)用獸用原料;化工原料;Building Blocks;Heterocyclic Building Blocks;Pyrimidines;Heterocyclic Compounds |
| Mol文件 | 68399-76-8.mol |
| 結(jié)構(gòu)式 |  |
乳清酸鋅二水合物 性質(zhì)
| 形態(tài) | 固體 |
|---|---|
| 顏色 | 白色至米白色 |
| InChI | 1S/2C5H4N2O4.2H2O.Zn/c2*8-3-1-2(4(9)10)6-5(11)7-3;;;/h2*1H,(H,9,10)(H2,6,7,8,11);2*1H2;/q;;;;+2/p-2 |
| InChIKey | KAXHRUFHOVCLAS-UHFFFAOYSA-L |
| SMILES | O.O.O=C1NC(=O)C=C(N1)C(=O)O[Zn]OC(=O)C2=CC(=O)NC(=O)N2 |
| LogP | -0.928 (est) |
| EPA化學(xué)物質(zhì)信息 | 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, zinc salt (2:1) (68399-76-8) |
Orotic acid (zinc)，一種嘧啶核苷酸和 RNA 生物合成的前體，從線粒體二氫乳清酸脫氫酶 (DHODH) 中釋放，通過細(xì)胞質(zhì) UMP 合酶轉(zhuǎn)化為 UMP。Orotic acid (zinc) 是尿素循環(huán)異常的常規(guī)新生兒篩查中的測量指標(biāo)。Orotic acid (zinc) 可引起大鼠肝脂肪變性和肝腫大。
Orotic acid is found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.
Orotic acid is a marker for measurement of urea cycle disorders (UCDs), including ornithine transcarbamylase deficiency (OTCD).
Orotic acid (1.0% addition to the diet; p.o. for 3-10 d) induces a development of fatty liver by day 7, and decreases purine/pyrimidine ratio of hepatic acid-soluble nucleotides by day 3.
安全信息
| 安全說明 | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| TSCA | TSCA listed |
| 存儲類別 | 11 - 可燃固體 |
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-N0157A | 乳清酸鋅二水合物 Orotic acid zinc | 68399-76-8 | 10 mg | 144元 |
| 2025/12/22 | HY-N0157A | 乳清酸鋅二水合物 Orotic acid zinc | 68399-76-8 | 25 mg | 211元 |