| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:VU0029251 CAS:330819-85-7 Purity:96% Package:1G;10G;100G
|
| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:VU0029251 CAS:330819-85-7 Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:VU0029251 CAS:330819-85-7 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 15002144251 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:VU0029251 CAS:330819-85-7 Package:1mg/RMB 659;5mg/RMB 2870;10mg/RMB 5170
|
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| | 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Basic information |
| Product Name: | 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine | | Synonyms: | 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine;5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine, 6,7-dihydro-2-(methylthio)-;10-Methylsulfanyl-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(12),2(6),8,10-tetraen-12-amine | | CAS: | 330819-85-7 | | MF: | C10H11N3S2 | | MW: | 237.34 | | EINECS: | | | Product Categories: | | | Mol File: | 330819-85-7.mol | ![3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Structure](CAS/20180720/GIF/330819-85-7.gif) |
| | 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 20mg/mL; PBS (pH 7.2): insolube | | form | A crystalline solid |
| | 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Usage And Synthesis |
| Description | VU0029251 is a partial antagonist of metabotropic glutamate receptor 5 (mGluR5; Ki = 1.07 μM).1 It inhibits calcium mobilization induced by glutamate in HEK293 cell membranes expressing rat mGluR5 (IC50 = 1.7 μM). | | Uses | VU0029251 is a mGluR5 partial antagonist (Ki: 1.07 μM). VU0029251 inhibits glutamate induced calcium mobilization in HEK293 cell membranes expressing rat mGluR5 (IC50: 1.7 μM)[1]. | | References | 1. Rodriguez, A.L., Grier, M.D., Jones, C.K., et al. Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity Mol. Pharmacol. 78(6),1105-1123(2010). |
| | 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Preparation Products And Raw materials |
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