Sartorypyrone B

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CAS:1452396-11-0
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Products Intro: Product Name:Sartorypyrone B
CAS:1452396-11-0
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CAS:1452396-11-0
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Company Name: Shanghai Saikerui Biotechnology Co. , Ltd.  
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CAS:1452396-11-0
Purity:NA Package:1mg Remarks:SCAK-101876
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Products Intro: Product Name:Sartorypyrone B
CAS:1452396-11-0
Purity:95% Package:1mg;5mg;10mg
Sartorypyrone B Basic information
Product Name:Sartorypyrone B
Synonyms:Sartorypyrone B;1H,11H-Phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one, 2,3-bis(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-, (2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)-rel-(-)-;(2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)-rel-(-)-2,3-bis(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-1H,11H-phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one
CAS:1452396-11-0
MF:C30H42O7
MW:514.65
EINECS:
Product Categories:
Mol File:1452396-11-0.mol
Sartorypyrone B Structure
Sartorypyrone B Chemical Properties
Boiling point 582.6±50.0 °C(Predicted)
density 1.19±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid
Safety Information
MSDS Information
Sartorypyrone B Usage And Synthesis
UsesSartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases[1].
Biological ActivitySartorypyrone B is a fungal metabolite that has been found in N. fischeri and has anticancer activity.1 It inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 μM, respectively).
References|1. Eamvijarn, A., Gomes, N.M., Dethoup, T., et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Tetrahedron 69(40), 8583-8591 (2013).
Sartorypyrone B Preparation Products And Raw materials
Tag:Sartorypyrone B(1452396-11-0) Related Product Information
Sartorypyrone D (+)-N-Methyl-3-(5,10,11,11a-tetrahydro-9-hydroxy-11-methoxy-8-methyl-5-oxo-1H-pyrrolo[2,1-c][1,4]benzodiazepine-2-yl)propenamide 2,4-Hexadien-1-one, 1-[(3aR,8aR,13bR,16R,16aS,17S)-17-[(2R)-3,3-dimethyl-2-oxiranyl]-2,3,8a,9,14,15-hexahydro-9-methyl-13,16-methano-8H,16H-pyrrolo[2',3':2,3]pyrido[4,3-o]quinindolin-1(16aH)-yl]-, (2E,4E)- 2-Propen-1-one, 1-[(2S,5S)-4-acetyl-2-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-5-(phenylmethyl)-1-piperazinyl]-3-phenyl-, (2E)- Sartorypyrone A