| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:AA9 TG2 inhibitor CAS:2134114-20-6 Package:1removed
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| Company Name: |
Biosynth Biological Technology (Suzhou) Co Ltd
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| Tel: |
51288865780 |
| Email: |
sales@biosynth.com |
| Products Intro: |
Product Name:Phenylmethyl N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]carbamate CAS:2134114-20-6
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Carbamic acid, N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester manufacturers
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| | Carbamic acid, N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester Basic information |
| | Carbamic acid, N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester Chemical Properties |
| Boiling point | 851.1±65.0 °C(Predicted) | | density | 1.226±0.06 g/cm3(Predicted) | | pka | 11.47±0.46(Predicted) |
| | Carbamic acid, N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester Usage And Synthesis |
| Description | AA9 is a novel transglutaminase (TG2) inhibitor. | | Uses | AA9 is a potent Transglutaminase 2 (TG2) inhibitor. AA9 strongly impacts HIF-mediated hypoxia in MDA-MB-231 cells[1]. | | References | [1] Ancona P, et al. Transcriptomics Studies Reveal Functions of Transglutaminase 2 in Breast Cancer Cells Using Membrane Permeable and Impermeable Inhibitors. J Mol Biol. 2024 May 15;436(10):168569. DOI:10.1016/j.jmb.2024.168569 |
| | Carbamic acid, N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester Preparation Products And Raw materials |
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