Tritiozine manufacturers
- Trithiozine
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- $68.00
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2026-06-06
- CAS:35619-65-9
- Purity: 99.82%
- Supply Ability: 10g
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| | Tritiozine Basic information |
| Product Name: | Tritiozine | | Synonyms: | Tritiozine;Sulmetozine;4-(3,4,5-Trimethoxythiobenzoyl)morpholine;4-[Thioxo(3,4,5-trimethoxyphenyl)methyl]morpholine;ISF-2001;morpholin-4-yl-(3,4,5-trimethoxyphenyl)methanethione;morpholino-(3,4,5-trimethoxyphenyl)methanethione;Methanethione, 4-morpholinyl(3,4,5-trimethoxyphenyl)- | | CAS: | 35619-65-9 | | MF: | C14H19NO4S | | MW: | 297.37 | | EINECS: | 2526454 | | Product Categories: | | | Mol File: | 35619-65-9.mol |  |
| | Tritiozine Chemical Properties |
| Melting point | 141-143° | | Boiling point | 420.8±55.0 °C(Predicted) | | density | 1.2461 (rough estimate) | | refractive index | 1.7500 (estimate) | | pka | 0.88±0.20(Predicted) | | form | Solid | | color | Off-white to light yellow |
| Toxicity | LD50 i.p. in mice: 2000 mg/kg (Pifferi, 1973) |
| | Tritiozine Usage And Synthesis |
| Uses | Trithiozine is an orally active antisecretory and antiulcer agent. Trithiozine can be used for the research of peptic ulcer disease and hypersecretory disorders[1]. | | Definition | ChEBI: Tritiozine is a member of methoxybenzenes. | | in vivo | Trithiozine (T) (i. p., oral, i. v.; 50 mg/kg, 200 mg/kg) shows a considerable antisecretory and antiulcer activity on different experimental models in the rats and dogs[1]. | Animal Model: | female Sprague-Dawley rats and male beagle dogs[1] | | Dosage: | 50 mg/kg (rats); 200 mg/kg or 50 mg/kg (dogs) | | Administration: | i. p., single (rats); oral, single or i. v. (dogs) | | Result: | Showed an apparent plasma half-life of about 2.5 h in rats and 1 h in dogs and rapidly metabolized yielding two metabolites and two conjugates. |
| | References | [1] G. M. Pacifici, et al. Pharmacokinetics and biotransformation, in rats and dogs, of trithiozine, a new antisecretory drug. , 1(3), 141–147. doi:10.1007/bf03189268. |
| | Tritiozine Preparation Products And Raw materials |
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