2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro-

2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro- Suppliers list
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Products Intro: Product Name:SHP2 inhibitor LY6
CAS:2296718-09-5
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Products Intro: Product Name:SHP2 inhibitor LY6
CAS:2296718-09-5
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Products Intro: Product Name:LY6
CAS:2296718-09-5
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Products Intro: CAS:2296718-09-5
Purity:98% HPLC Package:10mg;1g;10g;100g;1kg
Company Name: TargetMol Chemicals Inc.  
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Email: marketing@targetmol.cn
Products Intro: Product Name:SHP2 inhibitor LY6
CAS:2296718-09-5
Purity:99.19% Package:5mg/RMB 5630;25mg/RMB 11700;50mg/RMB 15300

2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro- manufacturers
2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro- Basic information
Product Name:2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro-
Synonyms:2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro-
CAS:2296718-09-5
MF:C30H27Cl2N3O4
MW:564.46
EINECS:
Product Categories:
Mol File:2296718-09-5.mol
2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro- Structure
2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro- Chemical Properties
density 1.389±0.06 g/cm3(Predicted)
pka6+-.0.50(Predicted)
Safety Information
MSDS Information
2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro- Usage And Synthesis
UsesSHP2 inhibitor LY6 (LY6) is potent and selective inhibitor of SHP2, with an IC50 of 9.8 μM. SHP2 inhibitor LY6 can inhibits SHP2-mediated cell signaling and proliferation[1].
References[1] Wu X, et, al. Small Molecule Inhibitor that Stabilizes the Autoinhibited Conformation of the Oncogenic Tyrosine Phosphatase SHP2. J Med Chem. 2019 Feb 14;62(3):1125-1137. DOI:10.1021/acs.jmedchem.8b00513
2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro- Preparation Products And Raw materials
Tag:2H-Benzimidazol-2-one, 1-[1-[[5-[(2E)-3-(2,4-dichlorophenyl)-1-oxo-2-propen-1-yl]-2-ethoxy-4-hydroxyphenyl]methyl]-1,2,5,6-tetrahydro-3-pyridinyl]-1,3-dihydro-(2296718-09-5) Related Product Information