MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE manufacturers
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| | MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Basic information |
| Product Name: | MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE | | Synonyms: | N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE;methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone;N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE;MEOSUC-APPV-CMK;MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE;MEOSUC-ALA-ALA-PRO-VAL-CMK;ELASTASE INHIBITOR III;HLE INHIBITOR | | CAS: | 65144-34-5 | | MF: | C22H35ClN4O7 | | MW: | 502.99 | | EINECS: | | | Product Categories: | ProteaseInhibitors | | Mol File: | 65144-34-5.mol |  |
| | MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Chemical Properties |
| Melting point | 159-161 °C | | Boiling point | 809.4±65.0 °C(Predicted) | | density | 1.234±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | ethanol: 50 mg/mL, clear, colorless | | pka | 13.05±0.20(Predicted) | | form | Solid | | color | white | | Sensitive | Moisture Sensitive | | BRN | 6167019 | | Sequence | {MeOSuc}-Ala-Ala-Pro-Val-{CMK} | | InChIKey | PJGDFLJMBAYGGC-XLPNERPQSA-N | | SMILES | COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)CCl |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 10 | | Storage Class | 11 - Combustible Solids |
| | MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Usage And Synthesis |
| Uses | A potent irreversible inhibitor of human leukocyte elastase | | Definition | ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone. | | General Description | N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor. | | Biochem/physiol Actions | N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE). |
| | MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Preparation Products And Raw materials |
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