- Corynoxine
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- $41.00
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2026-05-11
- CAS:6877-32-3
- Purity: 99.93%
- Supply Ability: 10g
- Corynoxine
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- $6.00
-
2020-03-10
- CAS:6877-32-3
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1kg, 5kg ,50kg
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| | Corynoxine Basic information |
| Product Name: | Corynoxine | | Synonyms: | (16E)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester;Corynoxine;Corynoxan-16-carboxylicacid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (16E)-;Corynoxine, 99.5%;Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'S,6'S,7'S,8'aS)-;(E)-methyl 2-((1'S,6'S,7'S,8a'S)-6'-ethyl-2-oxo-3',5',6',7',8',8a'-hexahydro-2'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate;Corynoxine, 10 mM in DMSO;Corynoxine A | | CAS: | 6877-32-3 | | MF: | C22H28N2O4 | | MW: | 384.47 | | EINECS: | 211-708-6 | | Product Categories: | | | Mol File: | 6877-32-3.mol |  |
| | Corynoxine Chemical Properties |
| Melting point | 166-168℃ | | Boiling point | 560.8±50.0 °C(Predicted) | | density | 1.23 | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 100 mg/mL (260.10 mM);Water : < 0.1 mg/mL (insoluble) | | pka | 13.61±0.60(Predicted) | | form | Cryst. | | color | White to off-white |
| | Corynoxine Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the Rubiaceae plant Uncaria rhynchophylla. | | Uses | Corynoxine is an indole alkaloid extracted from Uncaria plants, and have been shown to affect locomotor response in mice . Research points to a mediation of the central dopaminergic system. | | Definition | ChEBI: A natural product found in Uncaria macrophylla. | | in vivo | Corynoxine (100-100 mg/kg; oral gavage) exhibits prolongation of the thiopental-induced hypnosis in mice[2].
Corynoxine (10-100 μM for 12 h) induces autophagy in drosophila[1]. | | target | Akt | mTOR | Autophagy |
| | Corynoxine Preparation Products And Raw materials |
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