Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]-

Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Suppliers list
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Products Intro: Product Name:PD-1/PD-L1-IN-20
CAS:2159138-01-7
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Company Name: TargetMol Chemicals Inc.  
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Products Intro: Product Name:PD-1/PD-L1-IN-20
CAS:2159138-01-7
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Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- manufacturers

Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Basic information
Product Name:Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]-
Synonyms:Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]-;PD-1/PD-L1-IN-20
CAS:2159138-01-7
MF:C30H26BrClN2O3
MW:577.9
EINECS:
Product Categories:
Mol File:2159138-01-7.mol
Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Structure
Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Chemical Properties
Boiling point 721.5±55.0 °C(Predicted)
density 1.45±0.1 g/cm3(Predicted)
pka14.73±0.10(Predicted)
Safety Information
MSDS Information
Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Usage And Synthesis
UsesPD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
References[1] Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1.
Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Preparation Products And Raw materials
Tag:Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]-(2159138-01-7) Related Product Information
Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Acetamide, N-[2-[[[4-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-5-chloro-2-methoxyphenyl]methyl]amino]ethyl]- N-[2-[[[4-[(2-Bromo[1,1′-biphenyl]-3-yl)methoxy]-5-chloro-2-[(3-cyanophenyl)methoxy]phenyl]methyl]amino]ethyl]acetamide