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TargetMol Chemicals Inc.
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| Products Intro: |
Product Name:PD-1/PD-L1-IN-20 CAS:2159138-01-7 Package:1removed
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Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- manufacturers
- PD-1/PD-L1-IN-20
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- $1980.00
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2026-05-11
- CAS:2159138-01-7
- Purity:
- Supply Ability: 10g
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| | Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Basic information |
| | Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Chemical Properties |
| Boiling point | 721.5±55.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | pka | 14.73±0.10(Predicted) |
| | Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Usage And Synthesis |
| Uses | PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. | | References | [1] Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1. |
| | Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- Preparation Products And Raw materials |
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