| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HCV-IN-37
CAS:2425804-98-2
Package:100mg/RMB 17500;50mg/RMB 13800;25mg/RMB 10600
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Benzonitrile, 2-[[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]methyl]-4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)- manufacturers
- HCV-IN-37
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- $2500.00
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2026-04-20
- CAS:2425804-98-2
- Purity:
- Supply Ability: 10g
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| | Benzonitrile, 2-[[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]methyl]-4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)- Basic information |
| | Benzonitrile, 2-[[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]methyl]-4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)- Chemical Properties |
| Boiling point | 630.2±55.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | pka | 8.95±0.10(Predicted) |
| | Benzonitrile, 2-[[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]methyl]-4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)- Usage And Synthesis |
| Uses | HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage[1]. | | References | [1] Wang Y, et al. Design, Synthesis, and Biological Evaluation of 2-((4-Bisarylmethyl-piperazin-1-yl)methyl)benzonitrile Derivatives as HCV Entry Inhibitors. J Med Chem. 2022 Feb 10;65(3):2107-2121. DOI:10.1021/acs.jmedchem.1c01637 |
| | Benzonitrile, 2-[[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]methyl]-4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)- Preparation Products And Raw materials |
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