| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:DGKα-IN-2
CAS:2648556-92-5
Package:1removed
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1-Methyl-2-oxo-4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidyl]-1,2-dihydroquinoline-3-carboxamide manufacturers
- DGKα-IN-2
-
-
2026-05-11
- CAS:2648556-92-5
- Purity:
- Supply Ability: 10g
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| | 1-Methyl-2-oxo-4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidyl]-1,2-dihydroquinoline-3-carboxamide Basic information |
| | 1-Methyl-2-oxo-4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidyl]-1,2-dihydroquinoline-3-carboxamide Chemical Properties |
| Boiling point | 576.187±50.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.388±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | form | Solid | | pka | 14.716±0.20(predicted) | | color | White to off-white |
| | 1-Methyl-2-oxo-4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidyl]-1,2-dihydroquinoline-3-carboxamide Usage And Synthesis |
| Uses | DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study. | | References | [1] Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115. |
| | 1-Methyl-2-oxo-4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidyl]-1,2-dihydroquinoline-3-carboxamide Preparation Products And Raw materials |
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