| Company Name: |
Aquigen Bio science Pvt Ltd
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| Tel: |
+91-7030123794 |
| Email: |
archana.n@aquigenbio.com |
| Products Intro: |
Product Name:N-Deacetyl Apremilast CAS:253168-83-1 Purity:98% Package:100mg, 500mg, and 1gm
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| Company Name: |
JLS Laboratories Pvt Limited
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| Tel: |
+91 8790545679 |
| Email: |
bjreddy@jlslabs.in |
| Products Intro: |
Product Name:((S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (N- Deacetyl Apremilast) CAS:253168-83-1 Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
Chongqing Chemieliva Pharmaceutical Co., Ltd. Gold
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| Tel: |
18696571988 |
| Email: |
amy.lei@chemieliva.com |
| Products Intro: |
Product Name:1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- CAS:253168-83-1 Purity:98%
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| Company Name: |
Shanghai Kewel Chemical Co., Ltd.
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| Tel: |
021-64609169 18901607656 |
| Email: |
greensnown@163.com |
| Products Intro: |
Product Name:Apremilast Impurity 100 CAS:253168-83-1 Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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| | 1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Basic information |
| Product Name: | 1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- | | Synonyms: | 1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-;2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-aminoisoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 4-amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-;Apremilast Impurity 81;Apremilast Impurity 76;rac-Apremilast Impurity 11;4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione;((S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (N- Deacetyl Apremilast) | | CAS: | 253168-83-1 | | MF: | C20H22N2O6S | | MW: | 418.46 | | EINECS: | | | Product Categories: | | | Mol File: | 253168-83-1.mol | ![1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Structure](CAS/20150408/GIF/253168-83-1.gif) |
| | 1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Chemical Properties |
| Boiling point | 673.6±55.0 °C(Predicted) | | density | 1.383±0.06 g/cm3(Predicted) | | pka | -0.76±0.20(Predicted) | | InChI | InChI=1S/C20H22N2O6S/c1-4-28-17-10-12(8-9-16(17)27-2)15(11-29(3,25)26)22-19(23)13-6-5-7-14(21)18(13)20(22)24/h5-10,15H,4,11,21H2,1-3H3 | | InChIKey | BHJUWEUNUCJYER-UHFFFAOYSA-N | | SMILES | C1(=O)C2=C(C(N)=CC=C2)C(=O)N1C(C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O |
| | 1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Usage And Synthesis |
| Uses | 4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione is used in the apremilast acetylamino analogs preparation as oral PDE4 and TNF-α inhibitors. |
| | 1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Preparation Products And Raw materials |
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