GAMMA-SECRETASE INHIBITOR

GAMMA-SECRETASE INHIBITOR Suppliers list
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: +86-755-89396905 +86-15013857715
Email: admin@nexconn.com
Products Intro: Product Name:Z-LL-Nle-CHO
CAS:133407-83-7
Purity:98% Package:1KG;10KG;50KG
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:cbz-leucinyl-leucinyl-norleucinal
CAS:133407-83-7
Purity:99% Package:1kg
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:GAMMA-SECRETASE INHIBITOR
CAS:133407-83-7
Purity:99% Package:1KG;7USD
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:γ-Secretase Inhibitor I
CAS:133407-83-7
Package:100 mg Remarks:Please reach out to us for more information about custom solutions.
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Products Intro: Product Name:γ-Secretase Inhibitor I
CAS:133407-83-7
Purity:98% Min. Package:5KG;1KG

GAMMA-SECRETASE INHIBITOR manufacturers

  • Z-LLNle-CHO
  • Z-LLNle-CHO pictures
  • $2500.00
  • 2026-05-11
  • CAS:133407-83-7
  • Purity:
  • Supply Ability: 10g
GAMMA-SECRETASE INHIBITOR Basic information
Product Name:GAMMA-SECRETASE INHIBITOR
Synonyms:Z-LEU-LEU-NLE-ALDEHYDE;Z-LEU-LEU-NLE-CHO;Z-LLNLE-CHO;GAMMA-SECRETASE INHIBITOR;GAMMA-SECRETASE INHIBITOR I;Cbz-leucinyl-leucinyl-norleucinal;γ-Secretase Inhibitor I;L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formylpentyl]-
CAS:133407-83-7
MF:C26H41N3O5
MW:475.62
EINECS:
Product Categories:Alzheimers and Neurodegenerative Disease Research;gamma SecretaseNeurobiology;Neurodegenerative Disease Peptides;Other Alzheimer Peptides;Protease Inhibitor Specificity Index;Protease Inhibitors;R to;γSecretaseEnzyme Inhibitors by Enzyme;OtherNeuropeptides;Z-Leu-Leu-Nle-CHO;Pepetides;peptides
Mol File:133407-83-7.mol
GAMMA-SECRETASE INHIBITOR Structure
GAMMA-SECRETASE INHIBITOR Chemical Properties
storage temp. −20°C
solubility DMSO: soluble
form powder
color White to off-white
Sensitive Hygroscopic
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
GAMMA-SECRETASE INHIBITOR Usage And Synthesis
Usesgamma-Secretase Inhibitor I is a γ-secretase inhibitor.
Biological ActivityCell permeable: yes', 'Primary Target
γ-secretase', 'Product does not compete with ATP.', 'Reversible: no
in vivo

Z-LLNle-CHO (5 mg/kg; s.c.; single daily for 12 days) inhibits engraftment of B-lymphoblasts in precursor-B ALL xenograft model[2].

Animal Model:Female SCID/NOD mice (6-8-week-old; precursor-B ALL xenograft model)[2].
Dosage:5 mg/kg
Administration:Subcutaneous injection; single daily for 12 days
Result:Delayed or prevented engraftment of B-lymphoblasts in 50% of the animals comprising the experimental group.
GAMMA-SECRETASE INHIBITOR Preparation Products And Raw materials
Tag:GAMMA-SECRETASE INHIBITOR(133407-83-7) Related Product Information
γ-Secretase Inhibitor XXI DAPT DIBENZAZEPINE BETA-SECRETASE INHIBITOR IV N-Cbz-D-glutamic acid alpha-benzyl ester N-Carbobenzyloxy-L-alanine Z-D-ASP(OTBU)-OH H2O Z-NVA-OH Z-PHE-ALA-DIAZOMETHYLKETONE Z-SAR-OH GAMMA-SECRETASE INHIBITOR XVI GAMMA-SECRETASE INHIBITOR XV GAMMA-SECRETASE INHIBITOR XVII GAMMA-SECRETASE INHIBITOR XI GAMMA-SECRETASE INHIBITOR VII GAMMA-SECRETASE INHIBITOR X GAMMA-SECRETASE INHIBITOR XIX COMPOUND E