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| | AZURE A, CERTIFIED, PURE Basic information |
| Product Name: | AZURE A, CERTIFIED, PURE | | Synonyms: | AZURE A, CERTIFIED, PURE;AZURE A, CERTIFIED (C.I. 52005);AZURE A, FOR MICROSCOPY;AzurAForMicroscopy;AzurA(Macneal)C.I.52005;AZUR A FOR MICROSCOPY (C.I. No. 52005);Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-, chloride;PHENOTHIAZIN-5-IUM,3-AMINO-2-(DIMETHYLAMINO)-,CHLORIDE | | CAS: | 531-53-3 | | MF: | C14H14ClN3S | | MW: | 291.8 | | EINECS: | 208-510-7 | | Product Categories: | AHematology and Histology;Certified Stains&Dyes;Biochemicals and Reagents;A;Stains and Dyes;Stains&Dyes, A to;Detection;Fluorescent Probes, Labels, Particles and Stains;Phenothiazine | | Mol File: | 531-53-3.mol |  |
| | AZURE A, CERTIFIED, PURE Chemical Properties |
| Melting point | 290 °C (dec.)(lit.) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | H2O: soluble1mg/mL | | form | Powder | | Colour Index | 52005 | | color | Dark green | | Water Solubility | Soluble in water | | λmax | 620–634 nm | | ε(extinction coefficient) | ≥11000 at 242-246nm in H2O at -1
≥26000 at 287-291nm in H2O
≥34000 at 620-634μm in H2O | | Merck | 13,929 | | BRN | 3922287 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | Biological Applications | Antimalarial; medical devices; diagnosis of amyloid accumulation related diseases; reducing the extent of cardiac arrhythmias; treating angiogenic diseases,avian influenza virus,oral cavity infection,neurodegenerative diseases,pat | | Major Application | diagnostic assay manufacturing
hematology
histology | | InChI | 1S/C14H13N3S.ClH/c1-17(2)10-4-6-12-14(8-10)18-13-7-9(15)3-5-11(13)16-12;/h3-8,15H,1-2H3;1H | | InChIKey | NALREUIWICQLPS-UHFFFAOYSA-N | | SMILES | NC1=CC(SC(C2=N3)=CC(C=C2)=[N+](C)C)=C3C=C1.[Cl-] | | CAS DataBase Reference | 531-53-3(CAS DataBase Reference) | | EPA Substance Registry System | Azure A (531-53-3) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | SP5660000 | | TSCA | TSCA listed | | Storage Class | 11 - Combustible Solids |
| | AZURE A, CERTIFIED, PURE Usage And Synthesis |
| Chemical Properties | green to dark brown powder | | Uses | Biological stain. | | Uses | For staining cell granules and tissues | | Definition | ChEBI: An organic chloride salt having 3-amino-7-(dimethylamino)phenothiazin-5-ium as the counterion. It is used in making azure eosin stains for blood smear staining. | | Biological Activity | The combination of azure A and silver staining is used for the quantification of glycosaminoglycans in agarose gels. It is also used for the staining of chromosomes in the nucleus. Azure A is a main component of the azure B/polychromed methylene blue-eosin stains family, also referred to as the Romanowsky stain. Azure A is a basic cationic dye. | | Purification Methods | Azure A has been twice recrystallised from H2O and dried at 100o/1hour in an oven. [Beilstein 27 III/IV 5151.] |
| | AZURE A, CERTIFIED, PURE Preparation Products And Raw materials |
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