| Company Name: |
Shanghai Run-Biotech Co., Ltd.
|
| Tel: |
021-57171705 13817537615 |
| Email: |
sales@run-biotech.com |
| Products Intro: |
CAS:1279090-25-3
Purity:95% Package:5g
|
| Company Name: |
Henan Weituxi Chemical Technology Co., Ltd.
|
| Tel: |
0371-63284658 18135795563 |
| Email: |
3905209149@qq.com |
| Products Intro: |
Product Name:tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate
CAS:1279090-25-3
Purity:98% Package:100mg；500mg；1g;5g;25g
|
| Company Name: |
Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd
|
| Tel: |
0371-88900765 18037465274 |
| Email: |
3430974218@qq.com |
| Products Intro: |
Product Name:tert-butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate
CAS:1279090-25-3
Purity:95.00% Package:1g;5g;10g;50g;100g
|
| Company Name: |
Tianjin and Sinde Biotechnology Co., Ltd.
|
| Tel: |
15022315965; 18502259037 |
| Email: |
sales_hxd@163.com |
| Products Intro: |
Product Name:tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate
CAS:1279090-25-3
Purity:97% Package:1g；5g
|
|
| | tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate Basic information |
| Product Name: | tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate | | Synonyms: | tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate;tert-butyl N-[3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]oxetan-3-yl]carbamate;Carbamic acid, N-[3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-oxetanyl]-, 1,1-dimethylethyl ester | | CAS: | 1279090-25-3 | | MF: | C20H30BNO5 | | MW: | 375.27 | | EINECS: | | | Product Categories: | | | Mol File: | 1279090-25-3.mol |  |
| | tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate Chemical Properties |
| Boiling point | 490.3±45.0 °C(Predicted) | | density | 1.12±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 10.70±0.20(Predicted) | | Appearance | White to off-white Solid |
| | tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate Usage And Synthesis |
| Synthesis | Step 4: Preparation of tert-butyl {3-[4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]oxetan-3-yl}carbamate. Tert-butyl (3-(4-bromophenyl)oxetan-3-yl)carbamate (193 mg), pinacol ester of bis(boronic acid) (179 mg), and potassium acetate (173 mg) were dissolved in dimethyl sulfoxide (3 mL), PdCl2(dppf)CH2Cl2 (14 mg) was added, and degassed for 5 min. Subsequently, the reaction mixture was stirred at 80 °C for 5 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and filtered. The filtrate was washed with brine (5 times) and the organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure. Purification by column chromatography (eluent: 0-20% hexane solution of ethyl acetate) afforded the target product (189 mg, 86% yield).1H NMR (CDCl3, 400 MHz) δ: 7.85 (d, J = 8.3 Hz, 2H), 7.55 (d, J = 8.3 Hz, 2H), 5.29 (br s, 1H), 5.08-4.74 (m, 4H), 1.49-1.18 (m, 9H), 1.35 (s, 12H).LCMS: 376 [M + H]. | | References | [1] Patent: US2012/108574, 2012, A1. Location in patent: Page/Page column 116 |
| | tert-Butyl (3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetan-3-yl)carbamate Preparation Products And Raw materials |
|