| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Phellamurin
CAS:52589-11-4
Purity:96.5% Package:5mg Remarks:BBP00519
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phellamurin manufacturers
- Phellamurin
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- $166.00
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2026-05-11
- CAS:52589-11-4
- Purity: 97.91%
- Supply Ability: 10g
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| | phellamurin Basic information |
| Product Name: | phellamurin | | Synonyms: | phellamurin;(2R)-7-(β-D-Glucopyranosyloxy)-2,3-dihydro-3β,5-dihydroxy-2α-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;(dihydro) Phellodendron;4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-,(2R,3R)-;4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-, (2R,3R)-;(2R,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one;Cluster of differentiation 243,intestinal,anti-tumor,inhibit,MDR1,Pgp,CD243,glycoside,p-AKT,p-mTOR,p-PI3K,Multidrug resistance protein 1,P-glycoprotein,P-gp,ABCB1,Apoptosis,Flavonone,Phellamurin,Inhibitor;Phellamurin, 10 mM in DMSO | | CAS: | 52589-11-4 | | MF: | C26H30O11 | | MW: | 518.52 | | EINECS: | | | Product Categories: | | | Mol File: | 52589-11-4.mol |  |
| | phellamurin Chemical Properties |
| Boiling point | 861.5±65.0 °C(Predicted) | | density | 1.504±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 7.15±0.60(Predicted) | | color | Light yellow to yellow | | biological source | plant | | Water Solubility | water: slightly soluble | | Major Application | metabolomics
vitamins, nutraceuticals, and natural products | | InChIKey | GRDZTDZJQRPNCN-YIANMRPHSA-N | | SMILES | O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)Oc2c(c3c(c(c2)O)C(=O)[C@@H]([C@H](O3)c4ccc(cc4)O)O)CC=C(C)C |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | phellamurin Usage And Synthesis |
| Uses | Phellamurin is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. | | Definition | ChEBI: A member of the class of dihydroflavonols that is (+)-dihydrokaempferol substituted by a prenyl group at position 8 and a beta-D-glucopyranosyl group at position 7 via a glycosidic linkage. Isolated from Phellodend
on amurense and Commiphora africana, it exhibits inhibition of intestinal P-glycoprotein. | | Biological Activity | Phellamurin induces cells apoptosis, has anti-tumor activity, exhibits inhibition of intestinal P-glycoprotein and it has a role as a metabolite. | | in vivo | Phellamurin (50mg/kg/day; intraperitoneal injection; daily; for 21 days; female BALB/c nude mice) treatment represses osteosarcoma tumor growth in vivo. The ratios of p-PI3K/PI3K, p-AKT/AKT, and p-mTOR/mTOR are decreased in xenograft in Phellamurin-treated mice[1]. | Animal Model: | Athymic female BALB/c nude mice (6 weeks old ) injected with U2OS cells[1] | | Dosage: | 50mg/kg/day | | Administration: | Intraperitoneal injection; daily; for 21 days | | Result: | Repressed osteosarcoma tumor growth in vivo.
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| | target | P-gp |
| | phellamurin Preparation Products And Raw materials |
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