| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:JAK kinase-IN-1
CAS:2698389-43-2
Package:1removed
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JAK kinase-IN-1 manufacturers
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| | JAK kinase-IN-1 Basic information |
| Product Name: | JAK kinase-IN-1 | | Synonyms: | JAK kinase-IN-1;Methanone, [(1S)-2,2-difluorocyclopropyl][3-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-6-thia-3,8-diazabicyclo[3.2.1]oct-8-yl]- | | CAS: | 2698389-43-2 | | MF: | C17H19F2N7OS | | MW: | 407.44 | | EINECS: | | | Product Categories: | | | Mol File: | 2698389-43-2.mol |  |
| | JAK kinase-IN-1 Chemical Properties |
| Boiling point | 682.022±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.720±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 7.168±0.10(predicted) |
| | JAK kinase-IN-1 Usage And Synthesis |
| Uses | JAK kinase-IN-1 (Example 1) is a JAK inhibitor. JAK kinase-IN-1 inhibits TYK2, JAK1, JAK2 and JAK3 with IC50 values of 4.2 nM, 32 nM, 27 nM, 3473 nM respectively[1]. | | References | [1] Yao, Yuanshan, et al. Preparation of (pyrimidinyl)thiadiazabicyclo[3.2.1]octane derivatives as JAK kinase inhibitor and used for preventing and/or treating diseases or disorders related to JAK kinase activity or expression. Patent. WO2021180143. |
| | JAK kinase-IN-1 Preparation Products And Raw materials |
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