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| | 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE Basic information |
| Product Name: | 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE | | Synonyms: | 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE;1-isopropyl-1H-pyrazol-4-amine(SALTDATA: HCl);1-isopropyl-1H-pyrazol-4-amine 1HCl;4-AMINO-1-ISOPROPYL-1H-PYRAZOLE HCL;1-PROPAN-2-YLPYRAZOL-4-AMINE;4-Amino-1-(iso-propyl)pyrazole;1-(1-methylethyl)-1H-pyrazol-4-amine;1H-Pyrazol-4-amine, 1-(1-methylethyl)- | | CAS: | 97421-16-4 | | MF: | C6H11N3 | | MW: | 125.17 | | EINECS: | | | Product Categories: | | | Mol File: | 97421-16-4.mol |  |
| | 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE Chemical Properties |
| Boiling point | 234.2±13.0 °C(Predicted) | | density | 1.12±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 3.74±0.10(Predicted) | | Appearance | Brown to reddish brown Liquid |
| | 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 4-amino-1-isopropyl-1H-pyrazole from 1-isopropyl-4-nitro-1H-pyrazole: To a 25 mL round bottom flask was added a methanol solution (4 mL) of 1-isopropyl-4-nitro-1H-pyrazole (200 mg, 1.29 mmol, 1.00 equiv.) and palladium carbon (40 mg). Hydrogen (H2) was passed into the reaction system and the reaction was stirred for 3 hours at room temperature. Upon completion of the reaction, the solid catalyst was removed by filtration and the filtrate was concentrated in vacuum to afford 154 mg (95% yield) of 4-amino-1-isopropyl-1H-pyrazole as a pink oil. | | References | [1] Patent: WO2015/48281, 2015, A1. Location in patent: Paragraph 00510; 00512
[2] Patent: US2015/336982, 2015, A1. Location in patent: Paragraph 0301; 0303
[3] Patent: WO2017/4134, 2017, A1. Location in patent: Paragraph 00293
[4] Patent: WO2006/40520, 2006, A1. Location in patent: Page/Page column 123-124
[5] Patent: WO2007/99326, 2007, A1. Location in patent: Page/Page column 112 |
| | 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE Preparation Products And Raw materials |
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