7-胺基去乙酰氧基頭胞烷酸
| 中文名稱 | 7-胺基去乙酰氧基頭胞烷酸 |
|---|---|
| 中文同義詞 | 6-氨基屈;7-胺基去乙酰氧基頭胞烷酸;6-AMINOCHRYSENE,10NG/UL 標(biāo)準(zhǔn)品;化合物 T13519;6-氨基苯并菲;6-氨基丁烯;7-胺基去乙酰氧基頭胞烷酸,10 MM DMSO 溶液;7-胺基去乙酰氧基頭胞烷酸（標(biāo)準(zhǔn)品） |
| 英文名稱 | 6-AMINOCHRYSENE |
| 英文同義詞 | ADCA;6-Amc;Chrysenex;Chrysonex;6-CHRYSENAMINE;6-AMINOCHRYSENE;AMINOCHRYSENE;AMINOCHRYSENE, 6- |
| CAS號(hào) | 2642-98-0 |
| 分子式 | C18H13N |
| 分子量 | 243.3 |
| EINECS號(hào) | 220-149-7 |
| 相關(guān)類別 | |
| Mol文件 | 2642-98-0.mol |
| 結(jié)構(gòu)式 |  |
7-胺基去乙酰氧基頭胞烷酸 性質(zhì)
| 熔點(diǎn) | 209-211 °C(lit.) |
|---|---|
| 沸點(diǎn) | 376.18°C (rough estimate) |
| 密度 | 0.8933 (rough estimate) |
| 折射率 | 1.4500 (estimate) |
| 儲(chǔ)存條件 | 2-8°C |
| 溶解度 | 丙酮（微溶）、氯仿（微溶）、甲醇（微溶、加熱） |
| 酸度系數(shù)(pKa) | 4.32±0.30(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 黃色至棕色 |
| 水溶解性 | 155ug/L(24 ºC) |
| Merck | 13,2275 |
| CAS 數(shù)據(jù)庫(kù) | 2642-98-0(CAS DataBase Reference) |
6-Aminochrysene inhibits the hydroxylation of aniline, 0-demethylation of p-nitroanisole, and N-demethylation of aminopyrine by rat liver microsomes. Pre-treatment of rats with 6-aminochrysene markedly decreases the N-demethylation in vitro but significantly increases the hydroxylation and the 0-demethylation.
6-Aminochrysene is an inhibitor of the growth of several solid experimental tumours in vivo and has a cancerostatic effect on human breast cancer. Long term topical skin application of 6-Aminochrysene to mice induces development of benign skin tumors after 3 months and of skin malignancies after 7 months. Female mice respond earlier than males. Induction of skin tumors is more rapid when 6-Aminochrysene is applied ventrally instead of dorsally. Urinary excretion is about twice as high after skin application than after oral administration.
安全信息
| 危險(xiǎn)品標(biāo)志 | Xn |
|---|---|
| 危險(xiǎn)類別碼 | 22 |
| 安全說明 | 45-36/37/39-26 |
| WGK Germany | 3 |
| RTECS號(hào) | GC0500000 |
| 海關(guān)編碼 | 29214900 |
| 提供商 | 語言 |
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