2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester

2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Besifovir Dipivoxil maleate；LB80380 maleate
CAS:441785-26-8
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Shanghai Biopharmaleader Co., Ltd.  
Tel: +86 18721201413
Email: sales@biopharmaleader.com
Products Intro: Product Name:Besifovir
CAS:441785-26-8
Purity:98%HPLC Package:10g,100g
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester
CAS:441785-26-8
Purity:97.0% Package:5mg
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Email: market@ubiochem.com
Products Intro: Product Name:Besifovir Dipivoxil maleate
CAS:441785-26-8
Purity:5mg;10mg;50mg;100mg;250mg;500mg;1g Package:5mg;10mg;50mg;100mg;250mg;500mg;1g
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Email: cindy.huang@synzest.com
Products Intro: Product Name:Besifovir
CAS:441785-26-8
Purity:98% Package:10mg 100mg
2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester Basic information
Product Name:2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester
Synonyms:2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester;LB 80380;Propanoic acid, 2,2-dimethyl-, 1,1'-[[[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene)] ester;LB80380 maleate;PMCDG Dipivoxil;Besifovir Dipivoxil maleate (LB80380 maleate);Besifovir Dipivoxil maleate;Besifovir (PMCDG Dipivoxil
CAS:441785-26-8
MF:C22H34N5O7P
MW:511.508421
EINECS:
Product Categories:
Mol File:441785-26-8.mol
2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester Structure
2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester Chemical Properties
Safety Information
MSDS Information
2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester Usage And Synthesis
UsesBesifovir Dipivoxil (LB-80380), an analog of guanosine monophosphate, is an acyclic nucleotide phosphonate with antiviral effect. Besifovir Dipivoxil is rapidly converted by the liver and intestine to the intermediate metabolite LB80331 via the esterification process, subsequently phosphorylated into the di- and triphosphate forms, which act as antiviral DNA synthesis inhibitors. Besifovir Dipivoxil is promising for research of chronic hepatitis B[1].
References[1] Hwang JG, et al. Influence of Renal Function on the Single-Dose Pharmacokinetics of Besifovir, a Novel Antiviral Agent for theTreatment of Hepatitis B Virus Infection. J Clin Pharmacol. 2022 Jan;62(1):46-54. DOI:10.1002/jcph.1945
2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester Preparation Products And Raw materials
Raw materialsPHOSPHONIC ACID, [[[1-[(2-AMINO-9H-PURIN-9-YL)METHYL]CYCLOPROPYL]OXY]METHYL]- (9CI)-->Chloromethyl pivalate
Tag:2,2-Dimethylpropanoic acid [[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphinylidene]bis(oxymethylene) ester(441785-26-8) Related Product Information