- Propargyl-PEG3-COOtBu
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2026-07-24
- CAS:1374658-84-0
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG3-t-butyl ester Basic information |
| Product Name: | Propargyl-PEG3-t-butyl ester | | Synonyms: | Alkyne-PEG3-CH2CH2COOtBu;PROPARGYL-PEG3-CH2CH2COOTBU;Propargyl-PEG3-t-butyl ester;Propargyl-PEG3-COOtBu;Propargyl-PEG3-Boc;Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Propargyl-PEG3-t-Bu Ester;Propargyl-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | | CAS: | 1374658-84-0 | | MF: | C14H24O5 | | MW: | 272.34 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1374658-84-0.mol |  |
| | Propargyl-PEG3-t-butyl ester Chemical Properties |
| Boiling point | 337.2±27.0 °C(Predicted) | | density | 1.023±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, stored under nitrogen | | form | Liquid | | color | Colorless to light yellow |
| | Propargyl-PEG3-t-butyl ester Usage And Synthesis |
| Description | Propargyl-PEG3-t-butyl ester consists of an alkyne group and a t-butyl ester group. The alkyne groupreacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. The protected carboxyl group can be deprotected under acidic conditions. | | Uses | Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Propargyl-PEG3-t-butyl ester Preparation Products And Raw materials |
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