MCA-(ASN670,LEU671)-AMYLOID Β/A4 PROTEIN PRECURSOR770 (667-675)-LYS(DNP) AMIDE AMMONIUM SALT
| 中文名稱 | MCA-(ASN670,LEU671)-AMYLOID Β/A4 PROTEIN PRECURSOR770 (667-675)-LYS(DNP) AMIDE AMMONIUM SALT |
|---|---|
| 中文同義詞 | MCA-(ASN670,LEU671)-AMYLOID Β/A4 PROTEIN PRECURSOR770 (667-675)-LYS(DNP) AMIDE AMMONIUM SALT;熒光淬滅多肽MCA-SEVNLDAEFK(DNP)-NH2;熒光底物多肽Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide |
| 英文名稱 | Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770(667-675)-Lys(Dnp) amide ammonium salt |
| 英文同義詞 | Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770(667-675)-Lys(Dnp) amide ammonium salt;Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide;L-Lysinamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-;Mca-(Asn???,Leu??1)-Amyloid β/A4 Protein Precursor??? (667-675)-Lys(Dnp) amide ammonium salt;Mca-(Asn???,Leu???)-Amyloid β/A4 Protein Precursor??? (667-675)-Lys(Dnp) amide ammonium salt;Mca-SEVNLDAEFK(Dnp)-NH2;Mca-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide ammonium salt |
| CAS號 | 1802078-32-5 |
| 分子式 | C68H89N15O26 |
| 分子量 | 1532.54 |
| EINECS號 | |
| 相關(guān)類別 | |
| Mol文件 | 1802078-32-5.mol |
| 結(jié)構(gòu)式 |  |
MCA-(ASN670,LEU671)-AMYLOID Β/A4 PROTEIN PRECURSOR770 (667-675)-LYS(DNP) AMIDE AMMONIUM SALT 性質(zhì)
| 沸點 | 1895.0±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.395±0.06 g/cm3(Predicted) |
| 酸度系數(shù)(pKa) | 4.20±0.10(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 淺黃至黃色 |
| 序列 | {Mca}-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(Dnp)}-NH2 |
MCA-(ASN670,LEU671)-AMYLOID Β/A4 PROTEIN PRECURSOR770 (667-675)-LYS(DNP) AMIDE AMMONIUM SALT 用途與合成方法
Mca-SEVNLDAEFK (Dnp)-NH2 含有強熒光的 7-甲氧基香豆素基團，其通過共振能量轉(zhuǎn)移到 2,4 - 二硝基苯基而被有效猝滅。Mca-SEVNLDAEFK(Dnp)-NH2可以用來測量能夠在熒光基團和猝滅基團之間切割酰胺鍵的肽酶的活性，從而引起熒光的增加，比如用于檢測 BACE-1的活性。